| Project/Area Number |
21791254
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General surgery
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| Research Institution | The University of Tokushima |
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Principal Investigator |
TOBA Hiroaki The University of Tokushima, 大学院・ヘルスバイオサィエンス研究部, 助教 (40403745)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 移植外科学 / 肺再生医療 / 胎仔肺 / 気管支肺胞幹細胞 / 細胞移植 / ドナー |
|---|
| Research Abstract |
In our fetal lung implantation, donors could certainly survive and differentiate. Concerning the mechanism of survive of donors, the characteristics of fetal lung tissue and various transcriptional factor play important roles in embryonal lung morphogenesis. We demonstrated that TTF-1 plays a good role among them and donors can differentiate tracing normal lung morphogenesis. In contrast, cell implantation including the isolation of bronchioalveolar stem cells is on going project.
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