A novel molecular assay of lymph node metastases in breast cancer
| Project/Area Number |
21791264
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General surgery
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| Research Institution | 公益財団法人がん研究会 (2011)
Japanese Foundation For Cancer Research (2009-2010) |
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Principal Investigator |
OSAKO Tomo 公益財団法人がん研究会, 有明病院病理部, 研究員 (70535442)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 乳腺外科学 / 乳癌 / リンパ節転移 / 病理診断 / 分子生物学 / リンパ節転移診断 / サイトケラチン19 / mRNA / OSNA法 / 個別化医療 / 分子病理診断 / 臨床医学 / 乳線外科学 |
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| Research Abstract |
In breast cancer, the one-step nucleic acid amplification(OSNA) whole-node assay detects more lymph node metastases, particularly micrometastases than conventional histopathological examinations. Sentinel node tumor burden quantified using the OSNA assay predicts non-sentinel node metastases, particularly macrometastases.
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Report
(4 results)
Research Products
(25 results)
