Development of the novel molecular targeted therapy against hepatocellular carcinoma invasion and metastasis
Project/Area Number |
21791288
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Digestive surgery
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Research Institution | Hiroshima University |
Principal Investigator |
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Project Period (FY) |
2009 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 癌 / 遺伝子 / 蛋白質 / 細胞・組織 / 外科 |
Research Abstract |
The aim of this study was to develop the novel molecular targeted therapy against hepatocellular carcinoma invasion and metastasis. Although we were not able to clarify the clinical significance of expression of h-prune in hepatocellular carcinoma, we elucidated that h-prune frequently expressed in thyroid cancers and had an essential role in anaplastic thyroid cancer cell invasion and metastasis.
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Report
(4 results)
Research Products
(25 results)
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[Journal Article] Impact of pegylated interferon therapy on outcomes of patients with hepatitis C virus-related hepatocellular carcinoma after curative hepatic resection2012
Author(s)
Tanimoto Y, Tashiro H, Aikata H, Amano H, Oshita A, Kobayashi T, Kuroda S, Tazawa H, Takahashi S, Itamoto T, Chayama K, Ohdan H
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Journal Title
Ann Surg Oncol
Volume: 19
Issue: 2
Pages: 418-425
DOI
Related Report
Peer Reviewed
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[Journal Article] A huge metastatic liver tumor from leiomyosarcoma of the inferior vena cava : report of a case2011
Author(s)
Hashimoto M, Kobayashi T, Tashiro H, Amano H, Oshita A, Tanimoto Y, Kuroda S, Tazawa H, Aikata H, Chayama K, Fujii M, Arihiro K, Ohdan H
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Journal Title
Surg Today (Epub 30 Nov.)
Volume: (Epub)
Issue: 5
Pages: 505-508
DOI
NAID
Related Report
Peer Reviewed
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[Journal Article] Treatment strategy for early hepatocellular carcinomas : comparison of radiofrequency ablation with or without transcatheter arterial chemoembolization and surgical resection2011
Author(s)
Tashiro H, Aikata H, Waki K, Amano H, Oshita A, Kobayashi T, Tanimoto Y, Kuroda S, Tazawa H, Chayama K, Asahara T, Ohdan H
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Journal Title
J Surg Oncol
Volume: 104
Issue: 1
Pages: 3-9
DOI
Related Report
Peer Reviewed
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[Journal Article] Suppression of hepatocellular carcinoma recurrence after rat liver transplantation by FTY720, a sphingosine-1-phosphate analog.2009
Author(s)
Ushitora Y, Tashiro H, Ogawa T, Tanimoto Y, Kuroda S, Kobayashi T, Miyata Y, Itamoto, T, Asahara T, Ohdan H
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Journal Title
Transplantation 88
Pages: 980-986
Related Report
Peer Reviewed
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[Presentation] 高度脈管侵襲を伴う肝細胞癌に対する肝切除成績2011
Author(s)
小林剛、田代裕尊, 天野尋暢, 大下彰彦, 谷本新学, 田澤宏文, 黒田慎太郎, 楠部潤子, 藤國宣明, 相方浩, 大段秀樹.
Organizer
第23回日本肝胆膵外科学会・学術集会
Place of Presentation
東京
Year and Date
2011-06-10
Related Report
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