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Multifaceted study of gastrointestinal functions after pancreaticoduodenectomy.

Research Project

Project/Area Number 21791302
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Digestive surgery
Research InstitutionSapporo Medical University

Principal Investigator

AKIZUKI Emi  Sapporo Medical University, 医学部, 研究員 (20404626)

Research Collaborator HIRATA Koichi  札幌医科大学, 医学部, 教授 (50136959)
YASUTOSHI Kimura  札幌医科大学, 医学部, 講師 (80311893)
TAKAYUKI Nobuoka  札幌医科大学, 医学部, 助教 (50404603)
Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords膵臓外科学 / 膵頭十二指腸切除術 / 胃内容排出遅延 / 消化管機能 / 消化管生理 / 胃壁血流 / 術後合併症
Research Abstract

This study was planned to evaluate the post-pancreaticoduodenectomy (PD) oral intake tolerance. Perioperative data were prospectively collected in all patients, and the patient's postoperative dietary intake was recorded for all meals until discharge. The occurrence of delayed gastric emptying (DGE) and the amount of dietary intake were analyzed. The risk factors for low oral intake tolerance were additionally determined. As a result, gender (women), BMI (>25kg/m^2), postoperative intraabdominal infection, and DGE were significantly associated with low oral intake tolerance. Additionally, upper gastrointestinal contrast examination, and blood stream analysis by a CT Perfusion method were performed to study postoperative gastrointestinal functions. These results had possibilities to investigate the cause of postoperative low oral intake tolerance.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (19 results)

All 2010 2009

All Journal Article (10 results) (of which Peer Reviewed: 2 results) Presentation (9 results)

  • [Journal Article] 膵頭部癌に対するリンパ節郭清2010

    • Author(s)
      平田公一、木村康利、今村将史、奥谷浩一、山口洋志、秋月恵美、信岡隆幸、水口徹
    • Journal Title

      消化器外科 33(13)

      Pages: 1973-1983

    • Related Report
      2010 Final Research Report
  • [Journal Article] 膵嚢胞性疾患の新展開;IPMN術後残膵の病変 切除例、サベイランスを含め2010

    • Author(s)
      木村康利、秋月恵美, ほか
    • Journal Title

      肝・胆・膵

      Volume: 16巻3号 Pages: 459-467

    • Related Report
      2010 Annual Research Report
  • [Journal Article] リンパ節郭清 最近のコンセプト;膵頭部癌に対するリンパ節郭清2010

    • Author(s)
      平田公一、秋月恵美, ほか
    • Journal Title

      消化器外科

      Volume: 33巻13号 Pages: 1973-1983

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 膵・胆管癌における緩和医療の現況と展望;膵・胆道癌緩和医療におけるNSTの役割2010

    • Author(s)
      平田公一、秋月恵美, ほか
    • Journal Title

      胆と膵

      Volume: 31巻1号 Pages: 67-73

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 中・下部胆管癌切除症例の検討 予後因子としての胆管断端癌陽性のインパクト2009

    • Author(s)
      木村康利、永山稔、孫誠一、今村将史、秋月恵美、信岡隆幸、水口徹、古畑智久、平田公一
    • Journal Title

      胆道 23(5)

      Pages: 725-733

    • NAID

      10030360866

    • Related Report
      2010 Final Research Report
  • [Journal Article] 胆道癌の手術 中下部胆管癌の手術2009

    • Author(s)
      今村将史、木村康利、永山稔、秋月恵美、信岡隆幸、水口徹、古畑智久、平田公一
    • Journal Title

      消化器外科 32(11)

      Pages: 1747-1757

    • Related Report
      2010 Final Research Report
  • [Journal Article] Reconsideration of postoperative oral intake tolerance after pancreaticoduodenectomy: prospective consecutive analysis of delayed gastric emptying according to the ISGPS definition and the amount of dietary intake2009

    • Author(s)
      Akizuki E, Kimura Y, Nobuoka T, Imamura M, Nagayama M, Sonoda T, Hirata K
    • Journal Title

      Ann Surg 249(6)

      Pages: 986-994

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reconsideration of postoperative oral intake tolerance after pancreatic oduodenectomy : prospective consecutive analysis of delayed gastric emptying according to the ISGPS definition and the amount of dietary intake.2009

    • Author(s)
      Emi Akizuki
    • Journal Title

      Annals of Surgery 249(6)

      Pages: 986-994

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 【手術助手に求められるもの】膵頭十二指腸切除術2009

    • Author(s)
      平田公一、秋月恵美, ほか
    • Journal Title

      消化器外科 32-8

      Pages: 1335-1348

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 【胆道癌の診断と治療 最近の進歩】胆道癌の手術 中・下部胆管癌の手術2009

    • Author(s)
      今村将史、秋月恵美, ほか
    • Journal Title

      消化器外科 32-11

      Pages: 1747-1757

    • Related Report
      2009 Annual Research Report
  • [Presentation] 口演 CT Perfusionを用いた胃壁血流動態と膵頭十二指腸切除術後の経口摂取能の関連2010

    • Author(s)
      奥谷浩一、木村康利、今村将史、永山稔、秋月恵美、信岡隆幸、水口徹、古畑智久、平田公一
    • Organizer
      第72回日本臨床外科学会総会
    • Place of Presentation
      横浜
    • Related Report
      2010 Final Research Report
  • [Presentation] SY 幽門輪温存膵頭十二指腸切除術(PPPD)の位置づけを考える;SSPPDとの比較から2010

    • Author(s)
      秋月恵美、木村康利、永山稔、今村将史、信岡隆幸、目黒誠、川本雅樹、水口徹、古畑智久、平田公一
    • Organizer
      第65回日本消化器外科学会総会
    • Place of Presentation
      下関
    • Related Report
      2010 Final Research Report
  • [Presentation] OP 膵頭十二指腸切除術後感染性合併症の周術期因子の検討2010

    • Author(s)
      永山稔、木村康利、今村将史、秋月恵美、信岡隆幸、水口徹、古畑智久、平田公一
    • Organizer
      第110回日本外科学会定期学術集会
    • Place of Presentation
      名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] OP PD術後経口摂取能と胃壁血流動態の関係2010

    • Author(s)
      今村将史、木村康利、永山稔、秋月恵美、信岡隆幸、水口徹、古畑智久、平田公一
    • Organizer
      第110回日本外科学会定期学術集会
    • Place of Presentation
      名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] 幽門輪温存膵頭十二指腸切除術(PPPD)の位置づけを考える;SSPPDとの比較から2010

    • Author(s)
      秋月恵美
    • Organizer
      第65回日本消化器外科学会総会
    • Place of Presentation
      下関
    • Related Report
      2010 Annual Research Report
  • [Presentation] 膵頭十二指腸切除術後感染性合併症例の検討2009

    • Author(s)
      永山稔、木村康利、今村将史、秋月恵美、信岡隆幸、水口徹、平田公一
    • Organizer
      第22回日本外科感染症学会総会
    • Place of Presentation
      宇部
    • Related Report
      2010 Final Research Report
  • [Presentation] 膵頭十二指腸切除術後の胃壁血流評価と経口摂取能の解析2009

    • Author(s)
      今村将史、木村康利、永山稔、秋月恵美、信岡隆幸、水口徹、古畑智久、平田公一
    • Organizer
      第71回日本臨床外科学会総会
    • Place of Presentation
      京都
    • Related Report
      2010 Final Research Report
  • [Presentation] HP 上部消化管造影検査からみたPPPD術後DGE発症および経口摂取能の解析2009

    • Author(s)
      秋月恵美、木村康利、永山稔、孫誠一、信岡隆幸、今村将史、水口徹、古畑智久、平田公一
    • Organizer
      第109回日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Related Report
      2010 Final Research Report
  • [Presentation] 上部消化管造影検査からみたPPPD術後DGE発症および経口摂取能の解析2009

    • Author(s)
      秋月恵美
    • Organizer
      第109回日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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