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Temsirolimus, mTOR Inhibitor, Inhibits Progression of Malignant Pleural Mesothelioma in Vitro.

Research Project

Project/Area Number 21791316
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Thoracic surgery
Research InstitutionKanazawa University

Principal Investigator

TAMURA Masaya  Kanazawa University, 附属病院, 助教 (10397185)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords悪性胸膜中皮腫 / 分子標的治療 / PI3K-AKT-mTOR経路 / 悪性胸膜皮腫 / mTOR
Research Abstract

The results suggest the therapeutic efficacy of temsirolimus against MPM in vitro. And it is expected that temsirolimus inhibits MPM growth not only by anticancer effect but by antangiogenic effect in vivo.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (1 results)

All 2010

All Presentation (1 results)

  • [Presentation] 悪性胸膜中皮腫に対するmTORを標的とした分子標的治療の基礎的検討2010

    • Author(s)
      守屋真紀雄、田村昌也
    • Organizer
      第51回日本肺癌学会総会
    • Place of Presentation
      広島国際会議場(広島県)
    • Year and Date
      2010-11-22
    • Related Report
      2010 Annual Research Report 2010 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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