Temsirolimus, mTOR Inhibitor, Inhibits Progression of Malignant Pleural Mesothelioma in Vitro.
| Project/Area Number |
21791316
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | Kanazawa University |
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Principal Investigator |
TAMURA Masaya Kanazawa University, 附属病院, 助教 (10397185)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 悪性胸膜中皮腫 / 分子標的治療 / PI3K-AKT-mTOR経路 / 悪性胸膜皮腫 / mTOR |
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| Research Abstract |
The results suggest the therapeutic efficacy of temsirolimus against MPM in vitro. And it is expected that temsirolimus inhibits MPM growth not only by anticancer effect but by antangiogenic effect in vivo.
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Report
(3 results)
Research Products
(1 results)
