Cell Alive system indicated preferable result about preserving the heart for transplantation

• Project/Area Number: 21791317
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Thoracic surgery
• Research Institution: Kanazawa University
• Principal Investigator: YAMAGUCHI Syojiro Kanazawa University, 医学系, 協力研究員 (30436810)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 心移植 / 零度以下 / 長期心臓保存 / 微弱電磁場冷却装置 / 審度以下 / 心臓移植 / 心筋保護 / 微弱電磁場冷却

Research Abstract

As basic study, we searched the optimal degree of preserving the heart with the cell alive system(CAS). We found -5 Celsius was optimal degree. After that we researched the effects of CAS by using a Langendorff apparatus with rodents heart. With CAS group indicated superior result compared to control group in the ventricle function, myocardial edema, reserved ATP.