Histologic examinations of reconstructed and re-fused donors as for fetal rat lung implantation models

Research Project

Project/Area Number	21791325
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Thoracic surgery
Research Institution	The University of Tokushima
Principal Investigator	KENZAKI Koichiro The University of Tokushima, 病院, 講師 (70325265)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords	呼吸器外科学 / 胎仔肺 / 再生医療 / 肺再生/修復 / 肺組織移植 / ラットモデル / 肺再生 / 修復
Research Abstract	【Object】As for our fetal rat lung implantation models : We studied that the fine pieces of fetal lung tissues reconstructed and re-fused in the adult lung parenchyma using GFP (green fluorescent protein)-LEW and LEW rats.【Result】Fluorescence microscope : We clearly observed that the pieces of fetal lung tissues re-fused and communicated each other (GFP-LEW and LEW) in the adult LEW lung parenchyma at 1-4 weeks after implantation.