| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Research Abstract |
We performed pathological classification of primary medulloblastomas and examined molecules on the Wnt signal pathway by immunohistochemical and cytogenetic analyses. Pathologically, three patients were diagnosed with newly established subtype of medulloblastoma. Immunohistochemical cyclin D1 expression showed a trend of adverse outcome and all seven patients with cyclin D1 expression expired. On the contrary, γ-catenin expression correlated with good prognosis among the molecules analyzed. This research contributed to prognostic evaluation of medulloblastomas.
|
