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Brain neural circuit remodeling in the Olfactory system

Research Project

Project/Area Number 21791353
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Cerebral neurosurgery
Research InstitutionShinshu University

Principal Investigator

KAWAGISHI Kyutaro  Shinshu University, 医学部, 助教 (40313845)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords神経再生 / 神経機能再生 / 嗅覚
Research Abstract

Recovery of olfaction following the lateral olfactory tract (LOT) transection was examined in developing and adult animals. After complete LOT transection was made in P2 neonatal rats and 12w adult rats, olfactory discriminative ability was tested. Olfaction was well preserved in the P2 rat group, but not in the 12w adult rat group. These data indicate that neonatal rat brain has neural plasticity after brain injury resulting in re-establishment of olfactory neural circuit and preservation of olfactory function.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (6 results)

All 2011 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (4 results)

  • [Journal Article] Determination of functionally essential neuronal population of the olfactory epithelium for nipple search and subsequent suckling behavior in newborn rats.2009

    • Author(s)
      Kawagishi K, Moriizumi T., et.al.
    • Journal Title

      Brain Research 1267巻

      Pages: 50-57

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Determination of functionally essential neuronal population of the olfactory epithelium for nipple search and subsequent suckling behavior in newborn rats2009

    • Author(s)
      Kawagishi K, Moriizumi T., et.al
    • Journal Title

      Brain Research 1276

      Pages: 50-57

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 軸索切断による嗅球僧房細胞の細胞死の検討2011

    • Author(s)
      川岸久太郎, 他7名
    • Organizer
      第88回日本生理学会・第166回日本解剖学会 合同大会
    • Place of Presentation
      (Journal of Physiological Sciences抄録号誌上開催)
    • Year and Date
      2011-03-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 軸索切断による嗅球僧房細胞の細胞死の検討2011

    • Author(s)
      川岸久太郎, 他7名
    • Organizer
      第88回日本生理学会・第166回日本解剖学会 合同大会
    • Place of Presentation
      (震災により誌上開催に変更 Journal of Physiological Sciences抄録号 誌上開催)
    • Year and Date
      2011-03-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] NEURONAL POPULATION OF THE OLFACTORY EPITHELIUM FOR NIPPLE SEARCH AND SUBSEQUENT SUCKLING IN NEWBORN RATS.2009

    • Author(s)
      Kyutaro Kawagishi, et.al
    • Organizer
      IUPS(国際生理学会)
    • Place of Presentation
      京都
    • Year and Date
      2009-07-31
    • Related Report
      2010 Final Research Report
  • [Presentation] NEURONAL POPULATION OF THE OLFACTORY EPITHELIUM FOR NIPPLE SEARCH AND SUBSEQUENT SUCKLING IN NEWBORN RATS2009

    • Author(s)
      Kyutaro Kawagishi, et.al
    • Organizer
      IUPS(国際生理学会)
    • Place of Presentation
      京都
    • Year and Date
      2009-07-31
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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