Imaging of regional cerebral blood flow in the surrounding of cerebral infarction using laser speckle flowmetry system

Research Project

Project/Area Number	21791357
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Cerebral neurosurgery
Research Institution	Osaka University
Principal Investigator	NAKAMURA Hajime Osaka University, 医学部附属病院, 特任助教(常勤) (80533794)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords	脳血管障害 / 脳虚血 / イメージング / 皮質拡延性抑制 / 局所脳血流 / レーザースペックル脳表血流計 / ラット / cortical spreading depression / peri-infarct depolarization / レーザースペックル血流計
Research Abstract	Laser speckle flowmetry, a novel non-invasive live imaging system of regional cerebral blood flow, enabled us to visualize the propagation of peri-infarct depolarization (PID) in penumbra that has not been detected with conventional imaging systems as MRI and PET. This method revealed that PID propagates not only from core to periphery in radial fashion but also along the ischemic lesion circumferentially.

Report

(3 results)