Language function analysis using transcranial magnetic stimulation combined with machine learning of cerebral oscillatory changes.

• Project/Area Number: 21791360
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Cerebral neurosurgery
• Research Institution: Osaka University
• Principal Investigator: GOTO Tetsu Osaka University, 大学院・医学系研究科, 助教 (80533801)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
• Keywords: 脳磁図 / 脳律動変化 / 経頭蓋磁気刺激 / 言語機能

Research Abstract

In order to clarify the optimal condition of transcranial magnetic stimulation (TMS) for mapping language function, we measured neuromagnetic activities during performing language tasks, and analyzed time courses of brain activity localization. According to these results, we selected candidates of TMS parameters for inducing speech delay. The TMS of the inferior frontal gyrus were performed at five different timings in picture naming task. It is observed that a subject have a specific timing for inducing speech delay.

Research Products

• [Journal Article] Frequency-dependent Spatiotemporal Distribution of Cerebral Oscillatory Changes during Silent Reading : A Magnetoencephalograhic Group Analysis. (2011)
  • Author(s): Tetsu Goto, Masayuki Hirata, Yuka Umekawa, Takafumi Yanagisawa, Morris Shayne, Youichi Saitoh, Haruhiko Kishima, Shiro Yorifuji, Toshiki Yoshimine.
  • Journal Title: Neuroimage 54(1) Pages: 560-567
  • Peer Reviewed
• [Journal Article] Quantitative analysis of phosphenes induced by navigation-guided repetitive transcranial magnetic stimulation. (2011)
  • Author(s): Tani N, Hirata M, Motoki Y, Saitoh Y, Yanagisawa T, Goto T, Hosomi K, Kozu A, Kishima H, Yorifuji S, Yoshimine T.
  • Journal Title: Brain Stimul 4(1) Pages: 28-37
  • Peer Reviewed
• [Journal Article] Frequency-dependent Spatiotemporal Distribution of Cerebral Oscillatory Changes during Silent Reading : A Magnetoence phalograhic Group Analysis (2011)
  • Author(s): Tetsu Goto, Masayuki Hirata, Yuka Umekawa, Takafumi Yanagisawa, Morris Shayne, Youichi Saitoh, Haruhiko Kishima, Shiro Yorifuji, Toshiki Yoshimine
  • Journal Title: Neuroimage Volume: 54(1) Pages: 560-567
  • Peer Reviewed
• [Journal Article] Quantitative analysis of phosphenes induced by navigation-guided repetitive transcranial magnetic stimulation (2011)
  • Author(s): Tani N, Hirata M, Motoki Y, Saitoh Y, Yanagisawa T, Goto T, Hosomi K, Kozu A, Kishima H, Yorifuji S, Yoshimine T.
  • Journal Title: Brain Stimul. Volume: 4(1) Pages: 28-37
  • Peer Reviewed
• [Presentation] 皮質下脳波計測による神経白質線維の活動計 (2010)
  • Author(s): 後藤哲
  • Organizer: 第69回脳神経外科学会総会
  • Place of Presentation: 福岡
  • Year and Date: 2010-10-27
• [Presentation] 皮質下脳波計測による神経白質線維の活動計測 (2010)
  • Author(s): 後藤哲、平田雅之、橋本直哉、貴島晴彦、柳沢琢史、齋藤洋一、依藤史郎、吉峰俊樹
  • Organizer: 脳神経外科学会総会
  • Place of Presentation: 福岡
  • Year and Date: 2010-10-27
• [Presentation] Single trial classification of phonemes for electrocorticographic brain-machine interfaces. (2010)
  • Author(s): Goto T
  • Organizer: ICCN2010
  • Place of Presentation: 兵庫
  • Year and Date: 2010-10-03
• [Presentation] Single trial classification of phonemes for electrocorticographic brain-machine interfaces (2010)
  • Author(s): Tetsu Goto, Masayuki Hirata, Takufumi, Yanagisawa, Kojiro Matsushita, Morris Shayne, Hisao Sugata, Youichi Saitoh, Haruhiko Kishima, Shiro Yorifuji, Toshiki Yoshimine
  • Organizer: ICCN2010
  • Place of Presentation: 兵庫
  • Year and Date: 2010-10-03
• [Presentation] 単音発声時の皮質脳波を用いた単一施行推定 (2010)
  • Author(s): 後藤哲
  • Organizer: 包括型脳科学研究推進ネットワークワークショップ
  • Place of Presentation: 北海道
  • Year and Date: 2010-07-27
• [Presentation] 皮質脳波を用いた単音発声時の単一施行推定 (2010)
  • Author(s): 後藤哲
  • Organizer: 第12回日本ヒト脳機能マッピング学会
  • Place of Presentation: 東京
  • Year and Date: 2010-06-19
• [Presentation] 皮質脳波を用いた単音発声時の単一施行推定 (2010)
  • Author(s): 後藤哲、平田雅之、柳澤琢史、松下光次郎、シェインモリス、菅田陽怜、齋藤洋一、貴島晴彦、依藤史郎、吉峰俊樹
  • Organizer: ヒト脳機能マッピング
  • Place of Presentation: 東京
  • Year and Date: 2010-06-19
• [Presentation] Frequency-dependent Spatiotemporal Distribution of Cerebral Oscillatory Changes during Silent Reading: a Magnetoencepha lograhic Group Analysis (2010)
  • Author(s): 後藤哲
  • Organizer: Biomag 2010
  • Place of Presentation: Dubrovnik(クロアチア)
  • Year and Date: 2010-03-29
• [Presentation] Biomag2010 (2010)
  • Author(s): Goto T
  • Organizer: Frequency-dependent Spatiotemporal Distribution of Cerebral Oscillatory Changes during Silent Reading : A Magnetoencephalograhic Group Analysis.
  • Place of Presentation: Dubrovnik, Croatia
  • Year and Date: 2010-03-28
• [Presentation] 脳律動変化にもとづいた言語処理過程の開口合成脳磁図グループ解析 (2009)
  • Author(s): 後藤哲
  • Organizer: 第68回日本脳神経外科学会学術総会
  • Place of Presentation: 東京都
  • Year and Date: 2009-10-14
• [Presentation] 脳律動変化にもとついた言語処理過程の開口合成脳磁図グループ解析 (2009)
  • Author(s): 後藤哲
  • Organizer: 脳神経外科学会第68回学術総会
  • Place of Presentation: 東京
  • Year and Date: 2009-10-14
• [Presentation] 開口合成脳磁図による言語処理過程の画像化 (2009)
  • Author(s): 後藤哲
  • Organizer: 第24回生体磁気学会
  • Place of Presentation: 石川県
  • Year and Date: 2009-05-28