Identification of activated area after intraoperative transcranial electrical stimulation for motor evoked potential
| Project/Area Number |
21791368
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Kyushu University |
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Principal Investigator |
HASHIGUCHI kimiaki Kyushu University, 医学研究院, 助教 (80448422)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 機能脳神経外科学 / 運動誘発電位 / 経頭蓋電気刺激 / 被刺激部位 / 術中モニタリング / 運動機能 |
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| Research Abstract |
64 cases (Transcranial stimulation (TCS) : 29 cases, Direct cortical stimulation (DCS) : 35 cases) were included in this study. With increasing intensity from threshold level until 200 mA, the latency came to plateau, and no "jump" of latency was observed. The difference of latency between TCS and DCS was quite small. These results suggested that the activated area of TCS was almost same as far as the intensity is less than 200mA. The amplitude of MEPs after TCS with 200mA was much higher in the contralateral side compared to the ipsilateral, which suggested that the activated area was not brain stem but subcortex, where the bilateral cortico-spinal tract run distantly. In two cases in which significant deterioration of MEPs occur, postoperative contralateral palsies were observed. The corresponding lesions in these cases were internal capsula, which meant that the activated areas were subcortex which is proximal to the internal capsula. For TCS-MEP monitoring, the best intensity was thought to be the intensity needed for the supramaximal amplitude less than 200mA.
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Report
(3 results)
Research Products
(8 results)
