Evaluation of Articular Cartilage with High Frequency Ultrasound Imaging System

• Project/Area Number: 21791385
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Orthopaedic surgery
• Research Institution: Tohoku University
• Principal Investigator: HAGIWARA Yoshihiro 東北大学, 大学院・医学研究科, 講師 (90436139)
• Co-Investigator(Renkei-kenkyūsha): SAIJO Yoshifumi 東北大学, 大学院・医工学研究科, 教授 (00292277)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 関節軟骨 / 高周波超音波 / 非接触型組織評価 / 診断装置 / 高分解能 / 超音波顕微鏡 / 高解像度組織観察 / 非接触型組織観察 / 三次元組織観察 / 音速 / 弾性 / 組織評価 / 超音波 / 変形性関節症 / 関節拘縮 / ラット / 3次元組織評価

Research Abstract

A newly developed high-frequency ultrasound imaging system (HFUIS) provides noncontact high-resolution 3D ultrasound (US) imaging. A Transducer with central frequency of 120 MHz and a focal length of 3.2 mm was most appropriate for evaluating the articular cartilage. We divided the articular cartilage in three layers (superficial, middle and deep layers) and compare the images with those of scanning acoustic microscope (SAM). A high relative intensity by HFUIS and high sound speed area by SAM had strong correlations (Pearson product moment correlation, superficial layer: 0.704, middle layer: 0.731).

Research Products

• [Journal Article] Comparison of articular cartilage images assessed by high-frequency ultrasound microscope and scanning acoustic microscope (2012)
  • Author(s): Hagiwara Y, Saijo Y, Ando A, Onoda Y, Suda H, Chimoto E, Hatori K, Itoi E.
  • Journal Title: Int Orthop. Volume: 36(1) Pages: 185-90
• [Journal Article] Comparison of Articular Cartilage Images assessed by High Frequency Ultrasound Microscope and Scanning Acoustic Microscope (2012)
  • Author(s): Hagiwara Y, Saijo Y, Ando A, Onoda Y,Suda H, Chimoto E, Hatori K, Itoi E
  • Journal Title: International Orthopaedics Volume: 36 Pages: 185-190
  • Peer Reviewed
• [Presentation] Evaluation of Cartilage-Bone Complex Assessed by High Frequency Ultrasound Imaging System (2010)
  • Author(s): Hagiwara, Y; Ando, A; Saijo, Y; Onoda, Y; Suda, H; Hatori, K; Chimoto E; Itoi, E
  • Organizer: the ORS 56th Annual Meeting
  • Place of Presentation: New Orleans, Louisiana
• [Presentation] COMPARISON OF THE ARTICULAR CARTILAGE IMAGES WITH HIGH FREQUENCY ULTRASOUND MICROSCOPE AND SCANNING ACOUSTIC MICROSCOPE (2010)
  • Author(s): Yoshihiro Hagiwara, Akira Ando, Yoshito Onoda, Eiichi Chimoto, Yoshifumi Saijo, Hideaki Suda, Sonofuchi Kazuaki, Kanazawa Kenji, Eiji Itoi
  • Organizer: the 9th Congress of Asian Federation of Societies for Ultrasound in Medicine and Biology
  • Place of Presentation: New Delhi
• [Presentation] Evaluation of Cartilage-Bone Complex Assessed by High Frequency Ultrasound Imaging System (2010)
  • Author(s): Hagiwara Y, Ando A, Saijo Y, Onoda Y, Suda H, Hatori K, Chimoto E, Itoi, E
  • Organizer: the Orthopaedic Research Society 56th Annual Meeting
  • Place of Presentation: New Orleans, Louisiana USA
• [Presentation] EVALUATION OF CARTILAGE- BONE COMPLEX WITH HIGH FREQUENCY ULTRASOUND MICROSCOPE AND SCANNING ACOUSTIC MICROSCOPE (2009)
  • Author(s): Y. Hagiwara, A. Ando, Y. Saijo, K. Kobayashi, Y. Onoda, H. Suda, E. Chimoto, E, Itoi
  • Organizer: The 2009 World Congress on Osteoarthritis
  • Place of Presentation: Montreal, Canada
• [Presentation] EVALUATION OF CARTILAGE-BONE COMPLEX WITH HIGH FREQ UENCY ULTRASOUND MICROSCOPE AND SCANNING ACOUSTIC MICROSCOPE (2009)
  • Author(s): Y.Hagiwara, A.Ando, Y.Saijo, K.Kobayashi, Y.Onoda, H.Suda, E.Chimoto, E, Itoi, E
  • Organizer: The 2009 World Congress on Osteoarthritis
  • Place of Presentation: Motreal, Canada
• [Book] Acoustical Imaging, Volume 30, pp.119-124, Andre, Michael p.; Jones, Joie P.; Lee, Hua (Eds.) (2011)
  • Author(s): Hagiwara Y, Saijo Y, Ando A, Kobayashi K, Tanaka A, Hozumi, N, Hatori K, Itoi E
  • Total Pages: 399
  • Publisher: Springer