n vivo imaging of bone and soft tissue tumor using fluorescent antibody
Project/Area Number |
21791387
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Orthopaedic surgery
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Research Institution | Kanazawa University |
Principal Investigator |
HAYASHI Katsuhiro Kanazawa University, 附属病院, 助教 (80507054)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
Keywords | 骨・軟部腫瘍学 / 蛍光イメージング / 癌 / 外科 |
Research Abstract |
We have investigated in vivo imaging of bone and soft tissue tumor using fluorescent antibody. Osteosarcoma cells were stained with fluorescent anti-ALP antibody. For distinction of normal tissue, red or near-infrared wavelength was suitable. Osteosarcoma cells were transplanted into mice and ICG was intravenously administered. Tumor was visualized by ICG. It can be used for tumor resection guide. Further investigation would be considered, such as improvement of observation devices.
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Report
(3 results)
Research Products
(29 results)
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[Presentation] Real Time Imaging of Cancer Cell Seeding to the Lung in Live Mouse.2009
Author(s)
K Hayashi, H Tsuchiya, N Yamamoto, T Shirai, H Nishida, K Yamauchi, A Takeuchi, H Kimura, K Tomita, M Bouvet, RM.Hoffman.
Organizer
100th American Association for Cancer Research
Place of Presentation
Colorado Convention Center (USA)
Related Report
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