The role of macrophages in neuronal regeneration

Research Project

Project/Area Number	21791390
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Orthopaedic surgery
Research Institution	Hamamatsu University School of Medicine
Principal Investigator	SAWADA Tomokazu Hamamatsu University School of Medicine, 医学部付属病院, 助教 (10397375)
Research Collaborator	MIYAGI Michihito 浜松医科大学, 大学院生 (20467228)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000) Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	末梢神経 / 再生 / macrophage
Research Abstract	We sought to explore the role of macrophages in neuronal regeneration. There were no significant differences in the regeneration of the blood-nerve barrier (BNB) by selectively depleting the population of macrophages in nerve undergoing nerve compression injury. The influence of another factor is larger than macrophages for the regeneration of the BNB.