| Project/Area Number |
21791391
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Nagoya University |
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Principal Investigator |
TSUKUSHI Satoshi Nagoya University, 医学部附属病院, 病院助教 (90378109)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | Cross-relaxation Rate imaging / MRI / 骨軟部腫瘍 / 画像診断 / プロテオーム解析 |
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| Research Abstract |
In this study, a clear contrast was demonstrated between soft tissue tumors and adjacent muscle, fat, and bone, because the ECR of these tissues differ significantly. Since with ECRI free water protons exert no influence, the presence of tumor infiltration into the surrounding muscle and other subcutaneous tissues is clearly delineated, thereby greatly facilitating the setting of the resection line of soft tissue sarcomas preoperatively.
In breast cancer ECR-19 has been reported to show high values reflecting the degree of fibrosis, and in this study as well fibrous lesions such as DFSP and desmoids exhibited significantly higher ECR-19 values than did other tumors. This study suggested the possibility that ECR of soft tissue sarcomas may reveal various tumor characteristics.
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