Pathophysiology of steroid-induced osteonecorsis
| Project/Area Number |
21791402
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 骨壊死 / 骨壊死修復 / 大腿骨頭壊死症 / ステロイド性骨壞死 |
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| Research Abstract |
We assessed which part of the femoral head was the key point of a collapse, and also examined whether a collapsed region was associated with the size of necrotic lesion. Then, the results suggested that a collapse may begin at the lateral boundary of the necrotic lesion, and the size of the necrotic lesion seemed to contribute to the distribution of a collapse. We also examined the reparative process of osteonecrosis using SPECT/CT with 99mTc methylene diphosphonate. Then, during the time before collapse, there was a gradual increase in the tracer uptake around the necrotic lesion, shifting the main region from anteriorly to laterally.
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Report
(5 results)
Research Products
(35 results)
