| Project/Area Number |
21791428
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Asahikawa Medical College |
|---|
Principal Investigator |
KUROSAWA Atsushi Asahikawa Medical College, 医学部, 助教 (30463756)
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|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
|
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| Keywords | 麻酔学 / デクスメデトミジン / 血中濃度測定 / GC-MS |
|---|
| Research Abstract |
We established the method for measurement of plasma concentration of dexmedetomidine, a sedative medication widely used by intensive care units in Japan. We extracted dexmedetomidine with gas chromatography-negative ion chemical ionization mass spectrometry. The quantification of dexmedetomidine became possible by this method with diazepam as internal standard substance.
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