| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
In cultures with or without EGF (epidermal growth factor) which are main growth factors with a neural stem/progenitor cells in the postnatal cerebellum, Notch 1 and Jagged 1 express into these cells. When Notch signaling activated in these cells by overexpression of Notch intracellular domein (NICD), in HERP1, and 2 and HES1, the difference was not observed in the amount of revelation of the target gene. But Activation of Notch signaling increased HES5 in these cells.
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