| Project/Area Number |
21791470
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Anesthesiology/Resuscitation studies
|
|---|
| Research Institution | Wakayama Medical University |
|---|
Principal Investigator |
YOSHIMURA Seiko Wakayama Medical University, 医学部, 助教 (40468286)
|
|---|
| Research Collaborator |
TOKINAGA Yasuyuki 和歌山県立医科大学, 医学部, 助教 (60438281)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
|
|---|
| Keywords | カルシウムオシレーション / グルタミン酸 / アストロサイト / 揮発性麻酔薬 |
|---|
| Research Abstract |
Glutamatergic neurons have been one of the candidates for the target site of volatile anesthetics. It has been shown that astrocyte regulate the release of glutamate at synaptic cleft. This regulation is associated with calcium oscillation. The purpose of this study was to elucidate the relationship between calcium oscillation and glutamate release in the condition with or without volatile anesthetics. The result was no significant association because of the concentration of glutamate was vary widely.
|
