Voiding functions after orthotopic neobladder reconstruction in female bladder cancer patients and female continence mechanism

• Project/Area Number: 21791484
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Urology
• Research Institution: Hirosaki University
• Principal Investigator: KOIE Takuya Hirosaki University, 医学部附属病院, 講師 (60321965)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 膀胱癌 / 尿路変向術 / 排尿機能

Research Abstract

We investigated about voiding functions after orthotopic neobladder reconstruction in female bladder cancer patients and female continence mechanism. In our series, none of patients required catheterization for hypercontinence or residual urine. Our techniques for female bladder cancer patients are feasible. But we could not made clearly to urination mechanism with orthotopic neobladder in female patients.

Research Products

• [Journal Article] Invadopodia formation by bladder tumor cells. (2010)
  • Author(s): Sutoh M, Hashimoto Y, Koie T, et al.
  • Journal Title: Oncol Res 19 Pages: 85-92
  • Peer Reviewed
• [Journal Article] Core 2 N-acetylglucosaminyltransferase-1 expression induces aggressive potential of testicular germ cell tumor. (2010)
  • Author(s): Hatakeyama S, Kyan A, Koie T, et al.
  • Journal Title: Int J Cancer 127 Pages: 1052-1059
  • Peer Reviewed
• [Journal Article] Uterus-, fallopian tube-, ovary-, and vagina-sparing cystectomy followed by U-shaped ileal neobladder construction for female bladder cancer patients : oncological and functional outcomes. (2010)
  • Author(s): Koie T, Hatakeyama S, Yoneyama T, et al.
  • Journal Title: Urology 75 Pages: 1499-1503
  • Peer Reviewed
• [Journal Article] Surgical treatment of a giant liposarcoma in Japanese man. (2010)
  • Author(s): Hashimoto Y, Hatakeyama S, Koie T, et al.
  • Journal Title: Adv Urol 2010 Pages: 943073-943073
  • Peer Reviewed
• [Journal Article] Cauda equine symptoms are closely related to male lower urinary tract symptoms. (2010)
  • Author(s): Imai A, Yamamoto H, Koie T, et al.
  • Journal Title: Urol int 84 Pages: 325-329
  • Peer Reviewed
• [Journal Article] Risk factors for erectile dysfunction in healthy Japanese men. (2010)
  • Author(s): Imai A, Yamamoto H, Koie T, et al.
  • Journal Title: Int J Androl 33 Pages: 569-573
  • Peer Reviewed
• [Journal Article] 根治的膀胱全摘除術における手術部位感染の危険因子に関する検討:吸収糸による皮膚埋没縫合の有用性 (2010)
  • Author(s): 古家琢也, 山本勇人, 岡本亜希子, ほか
  • Journal Title: 泌尿紀要 55 Pages: 75-78
  • NAID: 120001192596
  • Peer Reviewed
• [Journal Article] 前立腺全摘除術標本における腫瘍体積とPSA再発との関連について (2010)
  • Author(s): 橋本安弘, 百瀬昭志, 古家琢也, ほか
  • Journal Title: 泌尿紀要 56 Pages: 91-94
  • Peer Reviewed
• [Journal Article] 膀胱癌における尿テロメラーゼ活性簡易測定法の有用性 (2010)
  • Author(s): 岩淵郁哉, 盛和行, 古家琢也, ほか
  • Journal Title: 泌尿紀要 56 Pages: 551-557
  • NAID: 120002576706
  • Peer Reviewed
• [Journal Article] Invadopodia formation by bladder tumor cells. (2010)
  • Author(s): Sutoh M, Hashimoto Y, Koie T
  • Journal Title: Oncol Res Volume: 19 Pages: 85-92
  • Peer Reviewed
• [Journal Article] Core 2 N-acetylglucosaminyltransferase-1 expression induces aggressive potential of testicular germ cell tumor. (2010)
  • Author(s): Hatakeyama S, Kyan A, Koie T
  • Journal Title: Int J Cancer Volume: 127 Pages: 1052-1059
  • Peer Reviewed
• [Journal Article] Uterus-, fallopian tube-, ovary-, and vagina-sparing cystectomy followed by U-shaped ileal neobladder construction for female bladder cancer patients : oncological and functional outcomes. (2010)
  • Author(s): Koie T, Hatakeyama S, Yoneyama T
  • Journal Title: Urology Volume: 75 Pages: 1499-1503
  • Peer Reviewed
• [Journal Article] Cauda equine symptoms are closely related to male lower arinary tract symptoms. (2010)
  • Author(s): Imai A, Yamamoto H, Koie T
  • Journal Title: Urol Int Volume: 84 Pages: 325-329
  • Peer Reviewed
• [Journal Article] Risk factors for erectile dysfunction in healthy Japanese men. (2010)
  • Author(s): Imai A, Yamamoto H, Koie T
  • Journal Title: Int J Androl Volume: 33 Pages: 569-573
  • Peer Reviewed
• [Journal Article] Uterus-, Fallopian Tube-, Ovary-, and Vagina-Sparing Cystectomy Follow ed by U-shaped Ileal Neobladder Construction for Female Bladder Cancer Patients : Oncological and Functional Outcomes (2010)
  • Author(s): 古家琢也, 他
  • Journal Title: Urology. (印刷中)
  • Peer Reviewed
• [Journal Article] An aggressive course of Xp11 translocation renal cell carcinoma in a 28-year-old man. (2009)
  • Author(s): Koie T, Yoneyama T, Hashimoto Y, et al.
  • Journal Title: Int J Urol 16 Pages: 333-335
  • NAID: 10025197225
  • Peer Reviewed
• [Presentation] Phase II trial of neoadjuvant gemcitabine and carboplatin for muscle-invasive bladder cancer followed by radical cystectomy. (2010)
  • Author(s): Koie T
  • Organizer: 第104回米国泌尿器科学会
  • Place of Presentation: モスコンセンター(サンフランシスコ)
  • Year and Date: 2010-05-28
• [Presentation] 「シンポジウム」 浸潤性膀胱癌周辺の話題「浸潤性膀胱癌周辺の話題-新膀胱up-to-date」 (2009)
  • Author(s): 古家琢也, 米山高弘, 橋本安弘, ほか
  • Organizer: 第74回日本泌尿器科学会東部総会
• [Presentation] 浸潤性膀胱癌周辺の話題「浸潤性膀胱癌周辺の話題-新膀胱 up-to-date (2009)
  • Author(s): 古家琢也, 他
  • Organizer: 第74回日本泌尿器科学会東部総会
  • Place of Presentation: 松本市
• [Presentation] Feasibility and efficacy of gemcitabine and carboplatin neoadjuvant chemotherapy in muscle-invasive bladder cancer.
  • Author(s): Koie T, Yamamoto H, Okamoto A, et al.
  • Organizer: 2009 ASCO Annual Meeting.
• [Presentation] Phase II trial of neoadjuvant gemcitabine and carboplatin for muscle-invasive bladder cancer followed by radical cystectomy.
  • Author(s): Koie T, Okamoto T, Tokui N, et al.
  • Organizer: 2010 AUA Annual Meeting
• [Presentation] A prospective phase II study of 6 months neoadjuvant LHRH agonist plus estramustine phosphate for high-risk prostate cancer followed by radical prostatectomy.
  • Author(s): Koie T, Okamoto T, Tokui N, et al.
  • Organizer: 2010 AUA Annual Meeting
• [Presentation] ワークショップ「手術指導と安全確保」 弘前大学におけるミニマム創根治的前立腺摘除術教育システム
  • Author(s): 古家琢也, 大山力
  • Organizer: 西日本泌尿器科学会総会2010
• [Presentation] Preoperative immunohistochemical detection of Core 2 β-1,6-N- acetylglucosaminyltransferase (C2GnT) predicts pathological stage and prostate-specific antigen relapse after radical prostatectomy.
  • Author(s): Koie T, Tokui N, Imanishi K, et al.
  • Organizer: The 6^<th> International Symposium on Hormonal Carcinogenesis 2010
• [Presentation] 回腸新膀胱における排尿機能の経時的変化-中長期成績における検討
  • Author(s): 古家琢也, 岡本哲平, 今西賢悟, ほか
  • Organizer: 第98回日本泌尿器科学会総会2010
• [Presentation] Core 2 N-acetylglucosaminyltransferase-1 (C2GnT-1) expression induces aggressive potential of testicular germ cell tumor
  • Author(s): Hatakeyama S, Kyan A, Koie T, et al.
  • Organizer: 第25回欧州泌尿器科学会2010
• [Presentation] Sequential chemotherapy for advanced bladder cancer with creatinine clearance 60ml/min or below.
  • Author(s): Yoneyama T, Suzuki Y, Koie T, et al.
  • Organizer: 2010 AUA Annual Meeting
• [Presentation] High risk前立腺癌に対するLH-RHアゴニスト+エストラムチンのネオアジュバント療法に関するPhase IIstudy
  • Author(s): 工藤茂将, 岡本哲平, 古家琢也, ほか
  • Organizer: 第98回日本泌尿器科学会総会2010
• [Remarks] ホームページ等