The risk of cigarette smoking for uterine cervical carcinogenesis among young Japanese population

Research Project

Project/Area Number	21791545
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Obstetrics and gynecology
Research Institution	Niigata University
Principal Investigator	NISHINO Koji Niigata University, 医歯学総合病院, 助教 (70447598)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000) Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	婦人科腫瘍学 / 子宮頸癌 / 喫煙 / 毒物代謝酵素遺伝子多型 / 癌抑制遺伝子メチル化
Research Abstract	In the current study, risk factors for developing cervical cancer were tobacco smoking and GSTM1 null. And inactivation of tumor-suppressor gene such as DAPK and FHIT through promoter hypermethylation is thought to be one of the mechanisms of carcinogenesis of the uterine cervix.

Report

(3 results)