The risk of cigarette smoking for uterine cervical carcinogenesis among young Japanese population
| Project/Area Number |
21791545
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Niigata University |
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Principal Investigator |
NISHINO Koji Niigata University, 医歯学総合病院, 助教 (70447598)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 婦人科腫瘍学 / 子宮頸癌 / 喫煙 / 毒物代謝酵素遺伝子多型 / 癌抑制遺伝子メチル化 |
|---|
| Research Abstract |
In the current study, risk factors for developing cervical cancer were tobacco smoking and GSTM1 null. And inactivation of tumor-suppressor gene such as DAPK and FHIT through promoter hypermethylation is thought to be one of the mechanisms of carcinogenesis of the uterine cervix.
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Report
(3 results)
Research Products
(1 results)
