| Project/Area Number |
21791566
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Nagasaki University |
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Principal Investigator |
MISHIMA Hiroyuki Nagasaki University, 大学院・医歯薬学総合研究科, COE研究員 (10513319)
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| Co-Investigator(Renkei-kenkyūsha) |
MIURA Kiyonori 長崎大学, 病院, 講師 (00363490)
阿部 修平 長崎大学, 大学院・医歯薬学総合研究科, 助教 (50549590)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 婦人科腫瘍学 / ヒトパピローマウイルス |
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| Research Abstract |
We hypothesized that the genomic structural variation of the defensin genes affects the individual variation of the cervical cancer susceptibility. Two groups, 200 patients with cervical cancer with persistent HPV infection and 200 control pregnant women, were compared in the distribution of genomic copy-number of the defensin genes. The results showed that the case samples have a tendency to be smaller in the copy-number of several defensin genes.
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