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Study for effects of combination of Intracytoplasmic sperm injection and artificial oocyte activation

Research Project

Project/Area Number 21791568
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Obstetrics and gynecology
Research InstitutionFukushima Medical University

Principal Investigator

SUGANUMA Ryota  福島県立医科大学, 医学部, 講師 (30528211)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords生殖医学 / 卵細胞質内精子注入法 / 体外受精 / 顕微授精 / 受精障害 / 人為的卵活性化法 / 人為的卵活性化
Research Abstract

Combination of ICSI and artificial oocytes activation immediately after ICSI was useful for infertility animals which spermatozoa were depress the sperm oocytes activation factors. Taking long time after ICSI in unactivated status(oocytes remains at MII) is caused to damage on sperm chromosomes and that is caused to worth embryos development. We suggest that activating oocytes at checking the presence of 2nd polar body might be useful for reduce damages, and that might be useful for"rescue"ICSI oocytes going to"unfertilized".

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (11 results)

All 2011 2010

All Journal Article (2 results) Presentation (7 results) Book (2 results)

  • [Journal Article] ICSI後受精障害に対する卵活性化法併用の影響に関する検討2011

    • Journal Title

      日本哺乳動物卵子学会誌

      Volume: 28(2) Pages: 22-22

    • Related Report
      2011 Final Research Report
  • [Journal Article] ICSI後受精障害に対する卵活性化法併用の影響に関する検討2011

    • Author(s)
      菅沼亮太
    • Journal Title

      日本哺乳動物卵子学会誌

      Volume: 28 Pages: 22-22

    • NAID

      10028124288

    • Related Report
      2011 Annual Research Report
  • [Presentation] ICSI後受精障害症例に対する卵活性化法併用の影響に関する検討2011

    • Author(s)
      菅沼亮太
    • Organizer
      第52回日本哺乳動物卵子学会
    • Place of Presentation
      栃木県大田原市
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation]2011

    • Organizer
      第52回日本哺乳動物卵子学会
    • Place of Presentation
      大田原市
    • Related Report
      2011 Final Research Report
  • [Presentation] 精子不動化処理方法の違いが、精子核に及ぼす影響についての検討2010

    • Author(s)
      菅沼亮太
    • Organizer
      第55回日本生殖医学会
    • Place of Presentation
      徳島市
    • Year and Date
      2010-11-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 凍結胚移植周期におけるアロマターゼ阻害薬の使用経験2010

    • Author(s)
      菅沼亮太
    • Organizer
      第48回日本生殖医学会・東北支部総会
    • Place of Presentation
      盛岡市
    • Year and Date
      2010-10-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] 凍結胚移植周期におけるアロマターゼ阻害薬の使用経験2010

    • Author(s)
      菅沼亮太
    • Organizer
      第13回福島リプロダクション研究会
    • Place of Presentation
      福島市
    • Year and Date
      2010-10-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 精子不動化処理方法の違いが、精子核に及ぼす影響についての検討2010

    • Author(s)
      菅沼亮太
    • Organizer
      第29回日本アンドロロジー学会
    • Place of Presentation
      東京都
    • Year and Date
      2010-07-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 精子不動化処理方法の違いが、精子核に及ぼす影響についての検討2010

    • Author(s)
      菅沼亮太
    • Organizer
      第51回日本哺乳動物卵子学会
    • Place of Presentation
      新潟市
    • Year and Date
      2010-05-29
    • Related Report
      2010 Annual Research Report
  • [Book] カラーアトラス不妊治療のための卵子学2010

    • Author(s)
      鈴木秋悦
    • Publisher
      編医歯薬出版株式会社
    • Related Report
      2011 Final Research Report
  • [Book] カラーアトラス不妊治療のための卵子学2010

    • Author(s)
      鈴木秋悦編
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2018-02-02  

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