Study for effects of combination of Intracytoplasmic sperm injection and artificial oocyte activation
| Project/Area Number |
21791568
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
SUGANUMA Ryota 福島県立医科大学, 医学部, 講師 (30528211)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 生殖医学 / 卵細胞質内精子注入法 / 体外受精 / 顕微授精 / 受精障害 / 人為的卵活性化法 / 人為的卵活性化 |
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| Research Abstract |
Combination of ICSI and artificial oocytes activation immediately after ICSI was useful for infertility animals which spermatozoa were depress the sperm oocytes activation factors. Taking long time after ICSI in unactivated status(oocytes remains at MII) is caused to damage on sperm chromosomes and that is caused to worth embryos development. We suggest that activating oocytes at checking the presence of 2nd polar body might be useful for reduce damages, and that might be useful for"rescue"ICSI oocytes going to"unfertilized".
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Report
(4 results)
Research Products
(11 results)
