Analysis of a new molecule target action of topotecan using a promoter microarray
| Project/Area Number |
21791578
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Obstetrics and gynecology
|
|---|
| Research Institution | Osaka Medical College |
|---|
Principal Investigator |
SASAKI Hiroshi Osaka Medical College, 医学部, 助教 (80432491)
|
|---|
| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | シスプラチン / トポテカン / プラチナ耐性 / Akt / NF・B / VEGF / 卵巣癌 / NFκB / NFкB |
|---|
| Research Abstract |
We revealed the mechanism that Topotecan reacquire the effect of cisplatin in platinum resistance ovarian cancer. Furthermore we revealed the mechanism of angiogenesis by cisplatin in platinum resistance ovarian cancer.
|
Report
(3 results)
Research Products
(13 results)
