Large-scale study on GJB2 gene mutation
| Project/Area Number |
21791585
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Hirosaki University |
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Principal Investigator |
NAMBA Atsushi Hirosaki University, 医学部附属病院, 助教 (50361027)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | GJB2 / 難聴 / 保因率 / 大規模研究 / 発生率 |
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| Research Abstract |
In the Iwaki Health Promotional Project executed on May 31st - June 8th of 2009, we collected blood samples from 832 participants and performed Pure-tone audiometry. Six GJB2 mutations were detected in 27 (7.54%) cases in the gene analysis performed on 358 samples from the participants. All of the 27 individuals were gene carriers and none had any symptoms. From this result the incidence of hearing loss caused by GJB2 mutation would be thought to be about 0.14%, higher than our previous assumption. We believe this high tendency may be a characteristic of this particular region.
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Report
(3 results)
Research Products
(1 results)
