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A new inner ear treatment utilizing anti TNF-α antibody

Research Project

Project/Area Number 21791587
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionHirosaki University

Principal Investigator

FUTAI Kazunori  Hirosaki University, 大学院・医学研究科, 客員研究員 (40431457)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
KeywordsTNF-α / 鼓室内投与 / 内耳再生 / 自己血清点耳
Research Abstract

It was thought that the whole body administration of the anti-TNF-α antibody to which the side effect happened frequently was improper as the mode of administration to the inner ear hair cells interruption, and the most effective technique was the direct administering to the inner ear by way of the fenestra rotunda. It was suggested that the transtympanic administration with an endoscope made the delivery of medicines into inner ears most easy and surely.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (9 results)

All 2010 2009 Other

All Presentation (8 results) Remarks (1 results)

  • [Presentation] 当院における自己血清点耳療法の使用経験2010

    • Author(s)
      二井一則
    • Organizer
      国立病院総合医学会
    • Place of Presentation
      福岡市
    • Year and Date
      2010-11-27
    • Related Report
      2010 Final Research Report
  • [Presentation] 当院における自己血清点耳療法の使用経験2010

    • Author(s)
      二井一則
    • Organizer
      日本耳科学会
    • Place of Presentation
      松山市
    • Year and Date
      2010-10-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 当院における自己血清点耳療法の使用経験2010

    • Author(s)
      二井一則
    • Organizer
      第20回日本耳科学会
    • Place of Presentation
      ひめぎんホール(松山市)
    • Year and Date
      2010-10-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Endoscopic transtynmpanic surgery in the treatment of conductive hearing loss, congenital cholesteatoma and adhesive otitis media2009

    • Author(s)
      Kazunori Futai
    • Organizer
      International conference on endoscopic ENT surgery
    • Place of Presentation
      グラース(フランス)
    • Year and Date
      2009-11-28
    • Related Report
      2010 Final Research Report
  • [Presentation] Endoscopic transtympanic surgery in the treatment of conductive hearing loss, congenital cholesteatoma and adhesive otitis media2009

    • Author(s)
      Kazunori Futai
    • Organizer
      ENDOSCOPIE ORL 2009
    • Place of Presentation
      グラース市(フランス)
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 外来経過中に人工耳小骨によるアブミ骨底板骨折を発症した1症例2009

    • Author(s)
      二井一則
    • Organizer
      日本耳科学会
    • Place of Presentation
      東京都
    • Year and Date
      2009-10-10
    • Related Report
      2010 Final Research Report
  • [Presentation] ENDOSCOPIC TRANSTYMPANIC SURGERY IN THE TREATMENT OF CONDUCTIVE HEARING LOSS, CONGENITAL CHOLESTEATOMA AND ADHESIVE OTITIS MEDIA2009

    • Author(s)
      Kazunori Futai
    • Organizer
      27^<th> Politzer Society Meeting
    • Place of Presentation
      ロンドン(イギリス)
    • Year and Date
      2009-09-03
    • Related Report
      2010 Final Research Report
  • [Presentation] 耳かき外傷による外傷性耳小骨離断の3症例2009

    • Author(s)
      二井一則
    • Organizer
      日本耳鼻咽喉科学会総会・学術講演会
    • Place of Presentation
      東京都
    • Year and Date
      2009-05-14
    • Related Report
      2010 Final Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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