Identification of responsible miRNAs associated with an acquired resistance for cis-diamminedichloroplatinum by microarray analyses in human head and neck squamous cell carcinoma
Project/Area Number |
21791588
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Otorhinolaryngology
|
Research Institution | Tohoku University |
Principal Investigator |
OGAWA Takenori Tohoku University, 病院, 助教 (50375060)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 癌 / マイクロアレイ / 薬剤反応性 / 薬剤応答性 |
Research Abstract |
The identification of the resistance-related microRNA clusters was conducted between RPMI2650CR and RPMI2650 using microRNA microarray. Furthermore, clinical study showed that miR34a could be a strong prognostic biomarker of CDDP treated sinonasal squamous cell carcinomas.
|
Report
(3 results)
Research Products
(22 results)