Genetic analysis in head and neck carcinomas in order to establish useful biomarkers
| Project/Area Number |
21791596
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 頭頸部外科学 / 頭頸部腫瘍 / 頭頸部癌 / 遺伝子解析 |
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| Research Abstract |
To improve the effectiveness of therapies in head and neck squamous cell carcinomas(HNSCCs), it is important to identify biomarkers related to clinical gain. In this research, we found dominancy of nonsense mutations in Japanese HNSCCs compared with other previous reports in the world. However, EGFR mutations, EGFR variant type III, ALK mutations, EML4-ALK fusions were not found in all the cases.
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Report
(4 results)
Research Products
(5 results)
