| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
We examined the role of B7-H3, which in the co-stimulating factor of B7 family, activated T lymphocyte in Head and Neck carcinoma. We verified the expression of B7-H3 slightly on Ca9-22 cell line of oral squamous cell carcinoma. CD44+cells are population of cancer stem like cells. I compared the B7-H3 expression on CD44+cell with CD44-cells. Moreover, we confirmed the expression of CD44 variant form is higher than CD44 standard form on Ca9-22. Ca9-22 hadn' t produced most of the TGF-beta.
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