Prevalence and clinical features of hearing loss patients with CDH23 mutations.
| Project/Area Number |
21791607
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Shinshu University |
|---|
Principal Investigator |
WAGATSUMA Michio 信州大学, 医学部・附属病院, 特任研究員 (00419409)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
MIYAGAWA Maiko 信州大学, 医学部・附属病院, 医員 (60467165)
NISHIO Shin-ya 信州大学, 医学部, 助教 (70467166)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
|---|
| Keywords | 感音難聴 / 内耳 / 遺伝性難聴 / CDH23 / 遺伝子 / スクリーニング / PCR / 家系調査 |
|---|
| Research Abstract |
CDH23 is likely to be an important cause for hearing loss patients but the prevalence of CDH23 mutation in Japanese hearing loss patient is not clear. To assess the importance of CDH23 mutations in non-syndromic hearing loss, two-step screening was applied and clinical characteristics of the patients with CDH23 mutations were examined in this study and found 26 possible pathogenic mutations.
|
Report
(4 results)
Research Products
(5 results)
