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Disturbed error monitoring of auditory processing in stuttering and neurorehabilitation

Research Project

Project/Area Number 21791620
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionKyushu University

Principal Investigator

OGATA Katsuya  九州大学, 医学研究院, 助教 (50380613)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords吃音 / 脳磁図 / 周波数解析 / エラー訂正障害 / 脳波 / エラー関連陰性電位 / ニューロリハビリテーション
Research Abstract

People who stutter(PWS) can reduce their stuttering rates under masking noise and altered auditory feedback ; such a response can be attributed to altered auditory input, which suggests that abnormal speech processing in PWS results from abnormal processing of auditory input. In order to characterize such abnormalities, we examined the functional changes in the auditory cortices of PWS using a 306-channel magnetoencephalography system. PWS exhibited impaired left auditory sensory gating(P50m suppression). The tonotopic organization in the right hemisphere ofPWS is expanded compared with that of the controls. The functional connectivity between both hemispheres were shown to be higher when sound was processed in the right hemisphere of PWS.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (12 results)

All 2011 2010 2009

All Journal Article (7 results) (of which Peer Reviewed: 4 results) Presentation (5 results)

  • [Journal Article] Spatiotemporal signatures of an abnormal auditory system in stuttering2011

    • Author(s)
      Kikuchi Y, Ogata K, Umesaki T, Yoshiura T, Kenjo M, Hirano Y, Okamoto T, Komune S, Tobimatsu S.
    • Journal Title

      Neuroimage

      Volume: 55 Pages: 891-899

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article] Transcranial direct current stimulation over the motor association cortex induces plastic changes in ipsilateral primary motor and somatosensory cortices2011

    • Author(s)
      Kirimoto H, Ogata K, Onishi H, Oyama M, Goto Y, Tobimatsu S.
    • Journal Title

      Clin Neurophysiol

      Volume: 122 Pages: 777-783

    • Related Report
      2011 Final Research Report
  • [Journal Article] Transcranial direct current stimulation over the motor association cortex induces plastic changes in ipsilateral primary motor and somatosensory cortices2011

    • Author(s)
      Kirimoto H, Ogata K, et al
    • Journal Title

      Clin Neurophysiol

      Volume: 122 Issue: 4 Pages: 777-83

    • DOI

      10.1016/j.clinph.2010.09.025

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spatiotemporal signatures of an abnormal auditory system in stuttering.2011

    • Author(s)
      Kikuchi Y, Ogata K, Umesaki T, Yoshiura T, Kenjo M, Hirano Y, Okamoto T, Komune S, Tobimatsu S
    • Journal Title

      Neuroimage

      Volume: 55 Pages: 891-899

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial direct current stimulation over the motor association cortex induces plastic changes in ipsilateral primary motor and somatosensory cortices.2011

    • Author(s)
      Kirimoto H, Ogata K, Onishi H, Oyama M, Goto Y, Tobimatsu S
    • Journal Title

      Clinical Neurophysiology

      Volume: 122 Pages: 777-783

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pre-movement gating of somatosensory-evoked potentials by self-initiated movements2009

    • Author(s)
      Ogata K, Okamoto T, Yamasaki T, Shigeto H, Tobimatsu S.
    • Journal Title

      The effects of ageing and its implication. Clinical Neurophysiology

      Volume: 120 Pages: 1143-1148

    • Related Report
      2011 Final Research Report
  • [Journal Article] Pre-movement gating of somatosensory-evoked potentials by self-initiated movements : The effects of ageing and its implication2009

    • Author(s)
      Ogata K; Okamoto T, Yamasaki T, et al.
    • Journal Title

      Clinical Neurophysiology 120

      Pages: 1143-1148

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Abnormal auditory latelarization in stuttering2011

    • Author(s)
      Kikuchi Y, Ogata K, et al
    • Organizer
      A magnetoencephalographic study. Society for Neuroscience
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2011-11-15
    • Related Report
      2011 Final Research Report
  • [Presentation] Abnormal auditory latelarization in stuttering : A magnetoencephalographic study2011

    • Author(s)
      Kikuchi Y, Ogata K, et al
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2011-11-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Cerebellar influence on spinal motoneurons using peristimulus time histogram2010

    • Author(s)
      Ogata K and Tobimatsu S.
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-30
    • Related Report
      2011 Final Research Report
  • [Presentation] Cerebellar influence on spinal motoneurons using peristimulus time histogram2010

    • Author(s)
      Ogata K, Tobimatsu S
    • Organizer
      29^<th> International Congress of Clinical Neurophysiology
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 運動前野への経頭蓋直流電流刺激による運動感覚連関の解明2009

    • Author(s)
      緒方勝也、飛松省三
    • Organizer
      第39回日本臨床神経生理学会学術集会
    • Place of Presentation
      北九州
    • Year and Date
      2009-11-18
    • Related Report
      2011 Final Research Report 2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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