Clarification of phase variation and severity of Streptococcus pneumoniae with acute otitis media.
Project/Area Number |
21791638
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Otorhinolaryngology
|
Research Institution | Wakayama Medical University |
Principal Investigator |
UENO Yumi Wakayama Medical University, 医学部, 博士研究員 (10445091)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 急性中耳炎 / 肺炎球菌 / フェーズ変化 / 耐性化 |
Research Abstract |
The rate of opaque-phase strains S.pneumoniae isolated from middle ear fluids of pediatric patients with acute otitis media were highly variable than that from nasopharynx. We evaluated clinical isolates from three cases with acute otitis media regarding to the phase variation and clonality of strains isolated from middle ear fluids and nasopharyngeal swabs. We observed the identical PFGE pattern on the strains showing different phase variation pattern in the middle ear fluid and in the nasopharynx.
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Report
(3 results)
Research Products
(4 results)