| Project/Area Number |
21791656
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Hyogo College of Medicine |
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Principal Investigator |
KATSURA Hirokazu Hyogo College of Medicine, 医学部, 助教 (90533761)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 鼓索神経 / 舌知覚 / 膝神経節 / 耳手術 / 味覚障害 / 鼓索神経切断モデル / 神経栄養因子 / 顔面神経 / 三叉神経節 / モノフィラメント圧痛計 / ディスククリミネーター |
|---|
| Research Abstract |
Patients often complain of taste disorder and tongue numbness after middle ear surgery. In the present study, postoperative trigeminal sensation of the tongue was examined by Sennes-Weinstein sensory test (SW test) and two-point discrimination tests. There were no significant differences on SW test, two point discrimination tests or EGM although the threshold of each test was elevated after surgery. The expression of TRP family in Geniculate Ganglion was no significant after cholda tympanic nerve injury. There findings suggested that injury to the chorda tympani nerve during middle ear surgery induces trigeminal disorder together with taste disorder.
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