Cure development of anticancer agent sensitivity and the cancer stem cell in head and neck cancer
Project/Area Number |
21791660
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Otorhinolaryngology
|
Research Institution | 愛知県がんセンター (2011) Nagoya University (2009-2010) |
Principal Investigator |
SUZUKI Hidenori 愛知県がんセンター, 研究所・腫瘍病理学部, 研究員 (70470169)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 頭頸部外科学 / FDG-PET / FDG-PET/CT / 頭頸部癌 / 抗癌剤感受性 / 癌幹細胞 / 治療抵抗性 / 抗がん剤感受性 / 頭頚部癌 / Sox2 / 抗癌剤感受性試験 |
Research Abstract |
In oral squmous cell carcinoma, SUVmax was related with tumor thickness and depth of invasion. Tumors with SUVmax ≧12 showed shorter 3-year overall survival, greater tumor thickness and depth of invasion, and higher average Bcl-2 intensity. SUVmax is non-invasive and useful parameter for predicting patients’ prognosis.
|
Report
(4 results)
Research Products
(12 results)