Effect of light-stress for retinal degeneration in rat models

Research Project

Project/Area Number	21791696
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Ophthalmology
Research Institution	Sapporo Medical University
Principal Investigator	ISHIKAWA Futoshi Sapporo Medical University, 医学部, 講師 (00419962)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000) Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords	遺伝性網膜変性症 / 遺伝性網膜変性ラット / 光ストレス / アポトーシス促進因子 / アポトーシス抑制因子 / 青色光除去フィルター / ロドプシン / 網膜光傷害 / 青色光
Research Abstract	The effects of various light-induced stress on the retina were examined in the retinal degenerative rat models. The most important problem in this study was light-induced stress promotes photoreceptor cell survival and function in model rats. However, this beneficial effect was not found in this study.

Report

(3 results)