Effect of light-stress for retinal degeneration in rat models
| Project/Area Number |
21791696
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
ISHIKAWA Futoshi Sapporo Medical University, 医学部, 講師 (00419962)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 遺伝性網膜変性症 / 遺伝性網膜変性ラット / 光ストレス / アポトーシス促進因子 / アポトーシス抑制因子 / 青色光除去フィルター / ロドプシン / 網膜光傷害 / 青色光 |
|---|
| Research Abstract |
The effects of various light-induced stress on the retina were examined in the retinal degenerative rat models. The most important problem in this study was light-induced stress promotes photoreceptor cell survival and function in model rats. However, this beneficial effect was not found in this study.
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Report
(3 results)
Research Products
(5 results)
