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Comparative study of retinal structure and focal function in patients with amblyopia using optical coherence tomography, microperimeter and multifocal electroretinogram

Research Project

Project/Area Number 21791697
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Ophthalmology
Research InstitutionFukushima Medical University

Principal Investigator

MORI Takafumi  Fukushima Medical University, 医学部, 助教 (10381386)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords弱視 / 網膜断層像 / 微小視野 / 局所網膜電図
Research Abstract

The amblyopic eyes had lower sensitivity in central visual field and larger fixational movements compared to the normal eyes. Also functions of the amblyopic eyes were inferior to those of the normal eyes, even if the amblyopic eyes got good visual acuity by treatment. In patients with anisometropic amblyopia, central retina were thinner and amplitudes of focal electroretinogram were lower in the amblyopic eye compared to the normal eyes. It suggests that density of photoreceptor cells is lower in the amblyopic eye. There was a positively correlation between amplitudes of focal electroretinogram and sensitivity of microperimeter, I consider that density or activity of photoreceptor cells affect visual function in patients with amblyopia.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (4 results)

All 2011 2010

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results)

  • [Journal Article] 3歳児検診要精査児の視力と屈折値2011

    • Author(s)
      森隆史, 齋藤かおり, 坂本章子, 丹治弘子, 橋本禎子, 八子恵子, 飯田知弘
    • Journal Title

      眼科臨床医報 4

      Pages: 240-244

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 3歳児健診要精査児の視力と屈折値2011

    • Author(s)
      森隆史
    • Journal Title

      眼科臨床医報

      Volume: 4 Pages: 240-244

    • NAID

      10031162525

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 不同視弱視の脈絡膜厚2010

    • Author(s)
      森隆史, 菅野幸紀, 小島彰, 丸子一朗, 橋本禎子, 八子恵子, 飯田知弘
    • Organizer
      第85回福島眼科集談会
    • Place of Presentation
      会津若松市
    • Year and Date
      2010-10-24
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Refractive errors in three-year-old children screening with Retinomax[○!R]2010

    • Author(s)
      Takafumi Mori, Kaori Saito, Hroko Tanji, Teiko Hashimoto, Keiko Yago, Tomohiro Iida.
    • Organizer
      The 25th Asia-Pacific Academy of Ophthalmology Congress
    • Place of Presentation
      北京・中華人民共和国
    • Year and Date
      2010-09-18
    • Related Report
      2010 Annual Research Report 2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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