Development of rejection-free corneal transplantation using cultured corneal endothelial cell

Research Project

Project/Area Number	21791698
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Ophthalmology
Research Institution	Yokohama City University
Principal Investigator	HAYASHI Takahiko Yokohama City University, 医学研究科, 特別研究員 (20527931)
Project Period (FY)	2009 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords	眼免疫学
Research Abstract	To resolve severe worldwide shortage of donors, we established a mouse model in which cultured allocorneal endothelium was transplanted onto a recipient mouse cornea. During the follow-up period, the transplanted cultured allo-corneal endothelium did not show any sign of allograft rejection. Realization of the clinical application of cultured allo-corneal endothelium transplantation may be a shortcut to ideal rejection-free corneal transplantation.

Report

(3 results)