Analysis of roles of glycosaminoglycans in keloid pathogenesis
Project/Area Number |
21791742
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Plastic surgery
|
Research Institution | Kyoto University |
Principal Investigator |
YAMAWAKI Satoko Kyoto University, 医学研究科, 時間雇用教職員 (70378777)
|
Project Period (FY) |
2009 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | ケロイド / 糖鎖 / GAG |
Research Abstract |
Excess accumulation of dermatan sulfate and chondoitin sulfate surrounding abnormal collagen bandles were found in keloid lesions. We propose that chondoitin sulfate plays a crucial role in the development of keloid lesions through the abnormal collagen fiber formation.
|
Report
(3 results)
Research Products
(13 results)