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Analysis of roles of glycosaminoglycans in keloid pathogenesis

Research Project

Project/Area Number 21791742
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Plastic surgery
Research InstitutionKyoto University

Principal Investigator

YAMAWAKI Satoko  Kyoto University, 医学研究科, 時間雇用教職員 (70378777)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsケロイド / 糖鎖 / GAG
Research Abstract

Excess accumulation of dermatan sulfate and chondoitin sulfate surrounding abnormal collagen bandles were found in keloid lesions. We propose that chondoitin sulfate plays a crucial role in the development of keloid lesions through the abnormal collagen fiber formation.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (13 results)

All 2010 2009 Other

All Journal Article (5 results) (of which Peer Reviewed: 1 results) Presentation (8 results)

  • [Journal Article] 甲賀病院におけるケロイド治療の現況2010

    • Author(s)
      山脇聖子
    • Journal Title

      公立甲賀病院紀要 13巻

      Pages: 81-85

    • Related Report
      2010 Final Research Report
  • [Journal Article] 甲賀病院におけるケロイド治療の現況2010

    • Author(s)
      山脇聖子
    • Journal Title

      公立甲賀病院紀要

      Volume: 13 Pages: 81-5

    • Related Report
      2010 Annual Research Report
  • [Journal Article] ケロイド・肥厚性瘢痕の手術療法2009

    • Author(s)
      山脇聖子、内藤素子
    • Journal Title

      PEPARS No.33

      Pages: 38-47

    • Related Report
      2010 Final Research Report
  • [Journal Article] ケロイド・肥厚性瘢痕の手術療法2009

    • Author(s)
      山脇聖子、内藤素子
    • Journal Title

      PEPARS 33

      Pages: 38-47

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Keloids can be forced into remission with surgical excision and radiation followed by adjuvant therapy

    • Author(s)
      山脇聖子, 他
    • Journal Title

      Ann Plast Surg (in press.)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] ケロイド肥厚性瘢痕の分類と評価2010

    • Author(s)
      山脇聖子、内藤素子
    • Organizer
      第4回瘢痕・ケロイド治療研究会(パネルディスカッション)
    • Year and Date
      2010-11-30
    • Related Report
      2010 Final Research Report
  • [Presentation] ケロイド肥厚性瘢痕の分類と評価2010

    • Author(s)
      山脇聖子
    • Organizer
      第4回瘢痕・ケロイド治療研究会(パネルディスカッション)
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肥厚性瘢痕・ケロイドの治療2010

    • Author(s)
      山脇聖子、内藤素子
    • Organizer
      平成2 年度日本形成外科学会秋季学術講習会
    • Year and Date
      2010-09-15
    • Related Report
      2010 Final Research Report
  • [Presentation] 肥厚性瘢痕・ケロイドの治療2010

    • Author(s)
      山脇聖子
    • Organizer
      平成22年度日本形成外科学会秋季学術講習会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] scar scaleによる術後2年間のケロイド治療成績評価2010

    • Author(s)
      山脇聖子、内藤素子
    • Organizer
      第2回日本創傷外科学会総会学術集会
    • Year and Date
      2010-07-30
    • Related Report
      2010 Final Research Report
  • [Presentation] scar scaleによる術後2年間のケロイド治療成績評価2010

    • Author(s)
      山脇聖子
    • Organizer
      第2回日本創傷外科学会総会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-07-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] ケロイド治療後の時系列評価の試み2010

    • Author(s)
      山脇聖子、内藤素子
    • Organizer
      第53回日本形成外科学会学術集会総会
    • Year and Date
      2010-04-07
    • Related Report
      2010 Final Research Report
  • [Presentation] ケロイド治療後の時系列評価の試み2010

    • Author(s)
      山脇聖子
    • Organizer
      第53回日本形成外科学会学術集会総会
    • Place of Presentation
      金沢
    • Year and Date
      2010-04-07
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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