Adiponectin improves survival rate of septic shock in mice model
| Project/Area Number |
21791764
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Emergency medicine
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
HARAGUCHI Go 東京医科歯科大学, 医学部・附属病院, 助教 (40361729)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 集中治療医学 / 敗血症 / 糖尿病 / 低アディポネクチン血症 / 集中治療と血糖 / アディポネクチン |
|---|
| Research Abstract |
Adiponectin transgenic mice were improved survival rate with septic shock compared to wild type mice. Furthermore adiponectin anti-sense transgenic mice, low adiponectin mice were worsened survival rate. Adiponectin suppressed inflammatory signaling in cells involving with septic shock progression.
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Report
(4 results)
Research Products
(3 results)
