Recruitment of masseter motoneurons by the presumed spindle Ia inputs.

• Project/Area Number: 21791804
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Functional basic dentistry
• Research Institution: Osaka University
• Principal Investigator: SATO Hajime Osaka University, 大学院・歯学研究科, 助教 (10432452)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
• Keywords: 口腔生理学 / 電気生理学 / 運動単位 / 序列動員 / 膜電位測定法 / 咬筋 / 咬合力

Research Abstract

Voltage-sensitive dye imaging revealed the recruitment of many MNs in the whole nucleus of masseter in response to repetitive stimulation at 100 Hz of the presumed spindle Ia inputs, which is visible in the slices that were obtained by cutting the brainstem at 15° tilted rostrally from the coronal plane. Illusion caused by vibration of primary sensory endings in human revealed a critical involvement of Ia inputs in regulating the orderly recruitment of masseter muscles.

Research Products

• [Journal Article] PKG dynamically modulates TASK1-mediated leak K+ currents in cholinergic neurons of the basal forebrain. (2010)
  • Author(s): Toyoda, H., Saito, M., Okazawa, M., Hirao, K., Sato H., Abe H., Takada K., Funabiki K., Takada M., Kaneko T. Kang, Y.
  • Journal Title: The Journal of Neuroscience. 30(16) Pages: 5677-5689
  • Peer Reviewed
• [Journal Article] Rank-ordered recruitment of masseter motoneurons. (2010)
  • Author(s): Kang, Y., Saito, M., Toyoda, H. Sato, H.
  • Journal Title: Journal of Oral Biosciences. 52(4) Pages: 330-335
  • Peer Reviewed
• [Journal Article] PKG dynamically modulates TASK1-mediated leak K^+ currents in cholinergic neurons of the basal forebrain. (2010)
  • Author(s): Toyoda, H., Saito, M., Okazawa, M., Hirao, K., Sato H., Abe H., Takada K., Funabiki K., Takada M., Kaneko T., Kang, Y.
  • Journal Title: The Journal of Neuroscience. Volume: 30(16) Pages: 5677-5689
  • Peer Reviewed
• [Journal Article] Rank-ordered recruitment of masseter motoneurons by the activity of mesencephalic trigeminal neurons during slow closing phase of mastication cycle (2010)
  • Author(s): Kang Y, Saito M, Toyoda H, Sato H
  • Journal Title: Journal of Oral Bioscience. Volume: 52(4) Pages: 330-335
  • Peer Reviewed
• [Journal Article] A rapid use-dependent downregulation of GABA(A) receptors in rat mesencephalic trigeminal neurons. (2009)
  • Author(s): Saito, M., Toyoda, H., Sato, H., Ishii, H. Kang, Y.
  • Journal Title: Journal of Neuroscience Research. 87(14) Pages: 3120-3133
  • Peer Reviewed
• [Journal Article] Rapid use-dependent down-regulation of gamma-aminobutyric acid type A receptors in rat mesencephalic trigeminal neurons. (2009)
  • Author(s): Saito M, Toyoda H, Sato H, Ishii H, Kang Y.
  • Journal Title: Journal of neuroscience research 87(14) Pages: 3120-3133
  • Peer Reviewed
• [Presentation] Differential electrophysiological properties of capsaicin-induced currents between layer II/III and layer V pyramidal cells of the insular cortex. (2011)
  • Author(s): 佐藤元, 川上晋平, 豊田博紀, 齋藤充, Yong-Chul Bae, 姜英男
  • Organizer: 第88回日本生理学会大会・第116回日本解剖学会総会全国学術集会 合同大会
  • Place of Presentation: (誌上にて)
  • Year and Date: 2011-03-28
• [Presentation] Electrophysiological properties of capsaicin-induced currents in layer II/III and layer V pyramidal cells of the insular cortex. (2010)
  • Author(s): Sato H, Kawakami S, Toyoda H, Saito M, Bae YC, Kang Y
  • Organizer: Neuroscience 2010
  • Place of Presentation: San Diego USA.
  • Year and Date: 2010-11-15
• [Presentation] Electrophysiological properties of capsaicin-induced currents in layer II/III and layer V pyramidal cells of the insular cortex. (2010)
  • Author(s): Sato H, Kawakami S, Toyoda H, Saito M, Bae YC, Kang Y
  • Organizer: Neuroscience 2010
  • Place of Presentation: San Diego USA
  • Year and Date: 2010-11-15
• [Presentation] カプサイシン投与により島皮質において誘発されるnetwork oscillation (2010)
  • Author(s): 佐藤元, 豊田博紀, 齋藤充, 姜英男
  • Organizer: 第103回近畿生理学談話会
  • Place of Presentation: 大阪
  • Year and Date: 2010-10-02
• [Presentation] カプサイシン投与により島皮質において誘発されるnetwork oscillation (2010)
  • Author(s): 佐藤元, 豊田博紀, 齋藤充, 姜英男
  • Organizer: 第103回 近畿生理学談話会
  • Place of Presentation: 大阪
  • Year and Date: 2010-10-02
• [Presentation] PKG modulates the recruitment of masseter motoneurons caused by the presumed spindle Ia inputs. (2009)
  • Author(s): Sato H, Saito M, Toyoda H, Kang Y.
  • Organizer: NEUROSCIENCE 2009
  • Place of Presentation: Chicago, USA.
  • Year and Date: 2009-10-21
• [Presentation] PKG modulates the recruitment of masseter motoneurons caused by the presumed spindle Ia inputs. (2009)
  • Author(s): Sato H, Saito M, Toyoda H, Kang Y.
  • Organizer: NEUROSCIENCE 2009
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-10-21
• [Presentation] Recruitment of masseter motoneurons by the presumed spindle Ia inputs. (2009)
  • Author(s): Sato H, Saito M, Toyoda H, Kang Y.
  • Organizer: IUPS 2009
  • Place of Presentation: Kyoto, Japan.
  • Year and Date: 2009-07-30
• [Presentation] Recruitment of masseter motoneurons by the presumed spindle Ia inputs. (2009)
  • Author(s): Sato H, Saito M, Toyoda H, Kang Y.
  • Organizer: IUPS 2009
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2009-07-30
• [Book] The Neural Challenge : Part I(Recruitment of masseter motoneurons by the presumed spindle Ia inputs, In : Breathe, Walk and Chew)(Progress in Brain Research)(Vol.187)(Gossard JP, Dubuc R, Kolta A, Eds.) (2010)
  • Author(s): Kang Y, Saito M, Toyoda H, Sato H.
  • Publisher: Elsevier, Amsterdam
• [Book] Interface Oral Health Science 2009(Recruitment of masseter motoneurons by spindle Ia inputs and its modulation by leak K^+ channels)(Sasano T, Suzuki O, Eds.) (2010)
  • Author(s): Kang Y, Toyoda H, Saito M, Sato H.
  • Publisher: Springer, Tokyo
• [Book] Breathe, Walk and Chew-The Neural Challenge : Part I (Progress in Brain Research, Vol.187) (2010)
  • Author(s): Kang Y, Saito M, Toyoda H, Sato H
  • Publisher: Elsevier, Amsterdam
• [Book] Interface Oral Health Science 2009 (2010)
  • Author(s): Kang Y, Saito M, Toyoda H, Sato H
  • Publisher: Springer, Tokyo
• [Remarks] ホームページ等
  • URL: http://www.dent.osaka-u.ac.jp/graduate/course/phys.html
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  • URL: http://www.dent.osaka-u.ac.jp/graduate/course/phys.html
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