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Analysis of the pre-motorneurons in the suckling rhythm generating network using a neonatal mouse brainstem-spinal cord preparation.

Research Project

Project/Area Number 21791814
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Functional basic dentistry
Research InstitutionShowa University

Principal Investigator

NAKAYAMA Kiyomi  Showa University, 歯学部, 助教 (00433798)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords吸啜 / 神経回路 / リズム形成 / マウス / 口腔生理学 / 顎運動
Research Abstract

Suckling movements play an important role to acquire the energy for living in the mammalians during postnatal period. The suckling movements are rhythmic movement evoked by tactile stimulation of the lip or the oral mucosa. It is known that the suckling rhythm is generated in neuronal networks in the brainstem, but kinds of interneurons involved in the neuronal networks are unclear. In the present study, we analyzed interneurons involved in the suckling rhythm generator using an isolated brainstem preparation from neonatal mice.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (16 results)

All 2011 2010 2009 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (12 results)

  • [Journal Article] Decreased intake of sucrose solutions in orexin knockout mice.2011

    • Author(s)
      Matsuo E, Mochizuki A, Nakayama K, Nakamura S, Yamamoto T, Shioda S, Sakurai T, Yanagisawa M, Shiuchi T, Minokoshi Y, Inoue T.
    • Journal Title

      J.Mol.Neurosci. 43

      Pages: 217-224

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Decreased intake of sucrose solutions in orexin knockout mice.2011

    • Author(s)
      Matsuo E, Mochizuki A, Nakayama K, Nakamura S, Yamamoto T, 他6名
    • Journal Title

      J.Mol.Neurosci.

      Volume: 43 Pages: 217-224

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Properties of synaptic transmission from the reticular formation dorsal to the facial nucleus to trigeminal motoneurons during early postnatal development in rats.2010

    • Author(s)
      Gemba-Nishimura A, Inoue T, Nakamura S, Nakayama K, Mochizuki A, Shintani S, Yoshimura S.
    • Journal Title

      Neuroscience 166

      Pages: 1008-1022

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Properties of synaptic transmission from the reticular formation dorsal to the facial nucleus to trigeminal motoneurons during early postnatal development in rats.2010

    • Author(s)
      Gemba A, Inoue T, Nakamura S, Nakayama K, Mochizuki A, Shintani S, Yoshimura S
    • Journal Title

      Neuroscience 166

      Pages: 1008-1022

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Neuronal mechanisms generating electrical stimulation-evoked rhythmic burst activity in the trigeminal nerve of eonatal mice.2011

    • Author(s)
      Nakayama K, Ihara Y, Inoue T.
    • Organizer
      Society for Neuroscience 40th annual meeting
    • Place of Presentation
      San Diego
    • Related Report
      2010 Final Research Report
  • [Presentation] Neuronal mechanisms generating electrical stimulation-evoked rhythmic burst activity in the trigeminal nerve of neonatal mice in vitro.2010

    • Author(s)
      Nakayama K, Ihara Y, Inoue T
    • Organizer
      Society for Neuroscience 40th Annual Meeting
    • Place of Presentation
      San Diego
    • Year and Date
      2010-11-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新生マウス脳幹摘出標本における三叉神経刺激誘発リズムに関与する神経伝達物質2010

    • Author(s)
      中山希世美、伊原良明、井上富雄
    • Organizer
      第33回 日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新生マウス脳幹摘出標本におけるリズミックな顎運動の誘発2010

    • Author(s)
      中山希世美、望月文子、西村晶子、井上富雄
    • Organizer
      日本顎口腔機能学会 第45回学術大会
    • Place of Presentation
      埼玉
    • Related Report
      2010 Final Research Report
  • [Presentation] 新生マウス脳幹摘出標本における三叉神経刺激誘発リズムに関与する神経伝達物質2010

    • Author(s)
      中山希世美、伊原良明、井上富雄
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Related Report
      2010 Final Research Report
  • [Presentation] 三叉神経中脳路核ニューロンにおけるオレキシンの作用2010

    • Author(s)
      中山希世美、望月文子、井上富雄
    • Organizer
      第7回GPCR研究会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] Effects of orexin on activities of mesencephalic trigeminal sensory neurons in developing rats.2009

    • Author(s)
      Inoue T, Nakayama K, Mochizuki A, Nakamura S, Shioda S.
    • Organizer
      Society for Neuroscience 39th annual meeting
    • Place of Presentation
      Chicago
    • Year and Date
      2009-10-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 新生マウス脳幹摘出標本における三叉神経刺激による顎運動の誘発2009

    • Author(s)
      中山希世美、伊原良明、井上富雄
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 新生マウス脳幹摘出標本において三叉神経の電気刺激により誘発される顎運動2009

    • Author(s)
      中山希世美、伊原良明、井上富雄
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] オレキシンの三叉神経中脳路核ニューロン活動に対する影響2009

    • Author(s)
      井上富雄、望月文子、中山希世美
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Related Report
      2010 Final Research Report
  • [Presentation] Rhythmic motor activity evoked by electrical stimulation of the trigeminal nerve sensory root in neonatal mice.

    • Author(s)
      Nakayama K, Ihara Y, Inoue T.
    • Organizer
      第88回日本生理学会 第116回日本解剖学会総会・全国学術集会 合同大会、会場での開催中止により誌上開催
    • Related Report
      2010 Final Research Report
  • [Presentation] Left and right coordination of NMDA-induced rhythmic activities in the trigeminal nerves of neonatal mice in vitro.

    • Author(s)
      Ihara Y, Nakayama K, Inoue T.
    • Organizer
      第88回日本生理学会 第116回日本解剖学会総会・全国学術集会 合同大会、会場での開催中止により誌上開催
    • Related Report
      2010 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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