The influence of immediate loading on bone around titanium implants with different surface topographies

• Project/Area Number: 21791876
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Prosthetic dentistry
• Research Institution: Tohoku University
• Principal Investigator: SATO Naoko Tohoku University, 大学院・歯学研究科, 助教 (80510015)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 早期荷重 / インプラント表面性状 / 骨結合

Research Abstract

To examine the interactive effects of mechanical loading and titanium surface topography on bone formation around immediately loaded implants, bone with loaded soomth(Sm) and acid-etched (AE) implants in rats were scanned by micro-CT system and removable torque test was performed. The loaded AE implants showed significantly decreased in bone mineral density of cortical bone at week 4 and contact surface area between cortical bone and the implant at week 2 compared to those for unloaded AE implants. The removable torque values for loaded Sm implants at week 1 was significantly lower than that for unloaded Sm implants although the loading didn't affect the biomechanical strength for AE implants. These suggested that different surface topography differently affected bone responses around immediately loaded implants.

Research Products

• [Journal Article] N-acetyl cysteine alleviate cytotoxity of bone substitute (2010)
  • Author(s): Yamada M, Ueno T, Minamikawa T, Sato N, Ogawa T
  • Journal Title: J Dental Res. 89 Pages: 411-416
  • Peer Reviewed
• [Journal Article] N-acetyl cysteine alleviates cytotoxity of bone substitute. (2010)
  • Author(s): Yamada M, Ueno T, Minamikawa, Sato N, Ogawa.T
  • Journal Title: J Dental Research Volume: Apr 89(4) Pages: 411-416
  • Peer Reviewed
• [Journal Article] Osteoblast mechanoresponse on Ti with different surface topographies (2009)
  • Author(s): Sato N, Kubo K, Yamada M, Hori N, Suzuki T, Maeda H, Ogawa T
  • Journal Title: J Dental Research Sep8 8(9) Pages: 812-816
  • Peer Reviewed
• [Journal Article] Age-dependent degradation of the protein adsorption capacity of titanium (2009)
  • Author(s): Hori N, Att W, Ueno T, Sato N, Yamada M, Saruwatari L, Suzuki. T, Ogawa. T
  • Journal Title: J Dental Research Jul8 8(7) Pages: 663-667
  • Peer Reviewed
• [Presentation] The influence of immediate loading on bone around titanium implants with different surface topographies. (2011)
  • Author(s): Kuwana T, Sato N, 他
  • Organizer: The 4^<th> International Symposium for Interface Oral Health Science
  • Place of Presentation: 仙台
  • Year and Date: 2011-03-08
• [Presentation] インプラント表面性状の違いによる即時荷重下の周囲骨動態 (2011)
  • Author(s): 桑名利江, 佐藤奈央子, 他
  • Organizer: 国際先端応用医科学研究会
  • Place of Presentation: 東京
  • Year and Date: 2011-01-22
• [Presentation] インプラント表面性状の違いによる即時荷重下の周囲骨動態 (2010)
  • Author(s): 桑名利江, 佐藤奈央子, 他
  • Organizer: 日本補綴歯科学会、東北-北海道支部学術大会
  • Place of Presentation: 札幌
  • Year and Date: 2010-10-24