Association between masticatory muscle, autonomic and cortical activity during sleep in animal model
| Project/Area Number |
21791888
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
KATO Takafumi Osaka University, 歯学研究科, 講師 (50367520)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 睡眠 / 咀嚼筋活動 / ブラキシズム / 律神経活動 / マイクロアローザル / ノンレム睡眠 / 大脳皮質 / 阻嚼筋活動 / 自律神経活動 / 三叉神経運動前ニューロン / α2アゴニスト / α2アビニスト |
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| Research Abstract |
Jaw muscle activities were associated with autonomic and cortical activation during NREM sleep. This association seems preserved when autonomic activity was pharmacologically suppressed. Cortical areas related to jaw motor control projected to the brainstem neurons such as trigeminal premotoneurons. Arousal activity such as c ortical and autonomic activations can be related to the genesis of jaw motor activity that might be further modulated under the influences of cortical descending inputs during NREM sleep.
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Report
(3 results)
Research Products
(45 results)
