• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

A research and development of novel low-cytotoxic oral self-care methods for the patients who use denture adhesives.

Research Project

Project/Area Number 21791898
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Prosthetic dentistry
Research InstitutionHiroshima University

Principal Investigator

HARADA Kae  Hiroshima University, 大学院・医歯薬学総合研究科, 助教 (60432663)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords口腔ケア / 義歯洗浄剤 / 洗口剤
Research Abstract

We first analyzed antimicrobial activity of ten kinds of commercial denture cleaner against Candida albicans by disk method. We examined eight kinds of home-care cleaners and two kinds of professional cleaners in this experimentation. Antimicrobial activity of every home-care cleaner was effective enough for clinical usage although it was lower than that of professional cleaners.
Moreover, we investigate removal activities of cream-type dental adhesives in five kinds of home care cleaners by soaping method. Removal effect in almost all of the cleaning agents was larger than purified water when soaking it for more than eighteen hours. However, we clinically use denture cleaner solution for less than twelve hours, so further studies are needed for the development of new denture cleaner which could remove denture adhesive more effectively.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (17 results)

All 2011 2010 2009

All Journal Article (2 results) Presentation (15 results)

  • [Journal Article] Autophagy induced by Staphylococcus aureus infection and bacterial proliferation in PRIP knockout cells.2010

    • Author(s)
      Harada, K., Kanematsu, T.
    • Journal Title

      J.Pharmacol.Sci. 112 Supplement I

      Pages: 217-217

    • Related Report
      2010 Final Research Report
  • [Journal Article] Autophagy induced by Staphylococcus aureus infection and bacterial proliferation in PRIP knockout cells.2010

    • Author(s)
      Harada, K., Kanematsu, T
    • Journal Title

      J.Pharmacol.Sci.

      Volume: 112 Pages: 217-217

    • Related Report
      2010 Annual Research Report
  • [Presentation] Energy metabolism is up-regulated in PRIP-DKO mice2011

    • Author(s)
      T.Okumura, K.Harada, N.Kamata, T.Kanematsu
    • Organizer
      The international workshop on BioDental Education and research 2011
    • Place of Presentation
      Hiroshima
    • Year and Date
      2011-01-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Energy metabolism is up-regulated in PRIP-DKO mice2011

    • Author(s)
      T.Okumura, K.Harada, N.Kamata, T.Kanematsu
    • Organizer
      The international workshop on BioDental Education and research 2011
    • Place of Presentation
      広島アステールプラザ
    • Year and Date
      2011-01-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 市販義歯洗浄剤の義歯安定剤に対する除去効果の評価2011

    • Author(s)
      原田佳枝、洪光、濱田泰三
    • Organizer
      第3回日本義歯ケア学会学術大会
    • Place of Presentation
      盛岡
    • Year and Date
      2011-01-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 市販義歯洗浄剤の義歯安定剤に対する除去効果の評価2011

    • Author(s)
      原田佳枝、洪光、濱田泰三
    • Organizer
      第3回日本義歯ケア学会学術大会
    • Place of Presentation
      岩手歯科大学
    • Year and Date
      2011-01-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] PRIPは細胞内に侵入したStaphylococcus aureusに対するオートファジーを調節する2010

    • Author(s)
      原田佳枝, 兼松隆
    • Organizer
      第33回日本分子生物学会, 第83回日本生化学会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Related Report
      2010 Final Research Report
  • [Presentation] PRIPは細胞内に侵入したStaphylococcus aureusに対するオートファジーを調節する2010

    • Author(s)
      原田佳枝, 兼松隆
    • Organizer
      第33回日本分子生物学会,第83回日本生化学会合同大会
    • Place of Presentation
      神戸コンベンションセンター
    • Year and Date
      2010-12-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規分子PRIPが仲介するエネルギー代謝調節機構の解明2010

    • Author(s)
      奥村俊哉, 原田佳枝, 鎌田伸之, 兼松隆
    • Organizer
      第49回広島県歯科医学会,第94回広島大学歯学会
    • Place of Presentation
      広島
    • Year and Date
      2010-10-24
    • Related Report
      2010 Final Research Report
  • [Presentation] 新規分子PRIPが仲介するエネルギー代謝調節機構の解明2010

    • Author(s)
      奥村俊哉, 原田佳枝, 鎌田伸之, 兼松隆
    • Organizer
      第49回広島県歯科医学会,第94回広島大学歯学会
    • Place of Presentation
      広島県歯科医師会館
    • Year and Date
      2010-10-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] Staphylococcus aureus感染が誘導するオートファジー形成にPRIPが関与する2010

    • Author(s)
      原田佳枝, 兼松隆
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Related Report
      2010 Final Research Report
  • [Presentation] Staphylococcus aureus感染が誘導するオートファジーにPRIPが関与する2010

    • Author(s)
      原田佳枝
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-03-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Phospholipase C-related inactive protein (PRIP) binds GEC1, a kappa opioid receptor binding protein2009

    • Author(s)
      T.Okumura, K.Harada, N.Kamata, T.Kanematsu
    • Organizer
      The 6th Japan-Korea Conference on Cellular Signaling for Young Scientists
    • Place of Presentation
      Sasebo
    • Year and Date
      2009-11-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Staphylococcus aureus infection-induced autophagy in phospholipase C-related inactive protein knockout cells2009

    • Author(s)
      K.Harada, T.Okumura, T.Kanematsu
    • Organizer
      The 6th Japan-Korea Conference on Cellular Signaling for Young Scientists
    • Place of Presentation
      Sasebo
    • Year and Date
      2009-11-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Staphylococcus aureus infection-induced autophagy in phospholipase C-related inactive protein knockout cells2009

    • Author(s)
      K.Harada, T.Okumura, T.Kanematsu
    • Organizer
      The 6^<th> Japan-Korea Conference on Cellular Signaling for Young Scientists
    • Place of Presentation
      ハウステンボス
    • Year and Date
      2009-11-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] PRIPを介したエネルギー代謝調節機構2009

    • Author(s)
      原田佳枝, 田中寛人, 平田雅人, 兼松隆
    • Organizer
      第51回日本歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-11
    • Related Report
      2010 Final Research Report
  • [Presentation] PRIPを介したエネルギー代謝調節機構2009

    • Author(s)
      原田佳枝, 田中寛人, 平田雅人, 兼松隆
    • Organizer
      第51回歯科基礎医学会学術大全ならびに総会
    • Place of Presentation
      朱鷺メッセ 新潟コンベンションセンター
    • Year and Date
      2009-09-11
    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi