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Development of tooth root distraction toward periodontal tissue regeneration with cementum and periodontal ligament.

Research Project

Project/Area Number 21791936
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Dental engineering/Regenerative dentistry
Research InstitutionNagoya University

Principal Investigator

ODA Tomoo  名古屋大学, 医学部附属病院, 講師 (10378002)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords再生歯学 / セメント質再生 / 歯根延長 / 超音波パルス / 仮骨延長法 / 歯周組織再生
Research Abstract

Osteotomy of alveolar bone with molar roots were carried out in the mandible of Japanese white rabbit. Distraction osteogenesis of alveolus and tooth roots was performed after distractor was put on the mandible. During distraction, mandible of the ultrasound group was treated with low-intensity pulsed ultrasound(LIPUS), and regeneration of cementum and periodontal ligament was observed in the lengthening site. Partial regeneration of dentin and pulp was radiographically observed contrary to our expectations, so that histological observation is attempted now.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (13 results)

All 2011 2010 2009

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (9 results) Book (1 results)

  • [Journal Article] Stability of a locking plate and self-drilling screws as orthodontic skeletal anchorage in the maxilla : a retrospective study.2010

    • Author(s)
      Hideharu Hibi, Kiyoshi Sakai, Tomoo Oda, Hisashi Hattori, Minoru Ueda, Masaru Sakai.
    • Journal Title

      Journal of Oral and Maxillofacial Surgery

      Volume: 68 Pages: 1783-1787

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of Cortical Bone Perforation on Periosteal Distraction : An Experimental Study in the Rabbit Mandible2009

    • Author(s)
      Tomoo Oda, Kazuhiko Kinoshita, Minoru Ueda.
    • Journal Title

      Journal of Oral and Maxillofacial Surgery

      Volume: 67 Pages: 1478-1485

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of Cortical Bone Perforation on Periosteal Distraction : An Experimental Study in the Rabbit Mandible2009

    • Author(s)
      Tomoo Oda, et al.
    • Journal Title

      Journal of Oral and Maxillofacial Surgery 67

      Pages: 1478-1485

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Treacher Collins症候群に伴う小下顎症に対して骨延長を施行した1例2011

    • Author(s)
      加納史也、小田知生、吉見涼子、木下一彦、服部宇、日比英晴、上田実
    • Organizer
      第56回日本口腔外科学会総会・学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2011-10-22
    • Related Report
      2011 Final Research Report
  • [Presentation] 幹細胞培養上清由来成長因子を用いたウサギ上顎洞挙上術モデルにおける骨形成性の検討2011

    • Author(s)
      木下一彦、片桐渉、大杉将嗣、八島明弘、健石英夫、小田知生、日比英晴、上田実
    • Organizer
      第56回日本口腔外科学会総会・学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2011-10-22
    • Related Report
      2011 Final Research Report
  • [Presentation] Treacher Collins症候群に伴う小下顎症に対して骨延長を施行した1例2011

    • Author(s)
      加納史也、小田知生, 他5名
    • Organizer
      第56回日本口腔外科学会総会・学術大会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 幹細胞培養上清由来成長因子を用いたウサギ上顎洞挙上術モデルにおける骨形成性の検討2011

    • Author(s)
      木下一彦、片桐渉、大杉将嗣、八島明弘、健石英夫、小田知生, 他2名
    • Organizer
      第56回日本口腔外科学会総会・学術大会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 口蓋に発生した筋上皮腫の1例2010

    • Author(s)
      井上崇徳、小田知生、服部宇、日比英晴、上田実
    • Organizer
      第55回日本口腔外科学会総会・学術大会
    • Place of Presentation
      幕張
    • Year and Date
      2010-10-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 機能性リコンビナントコラーゲンの基礎的研究第2報スキャフォールドとしての検討2009

    • Author(s)
      服部宇、浜村和紀、木下一彦、池野正幸、渋谷英伸、廣中克紀、小田知生、上田実
    • Organizer
      第54回日本口腔外科学会総会・学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2009-10-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 特異なX線像を呈した良性セメント芽細胞腫と単純性骨嚢胞が併発した1例2009

    • Author(s)
      高後友之、小田知生、服部宇、日比英晴、上田実
    • Organizer
      第54回日本口腔外科学会総会・学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2009-10-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Internal transport distraction for mandibular reconstruction2009

    • Author(s)
      Hideharu Hibi, Kazuhiko Kinoshita, Daiki Mizuno, Tomoo Oda, HisashiHattori, Minoru Ueda
    • Organizer
      13th Biennial International Congress Incorporating the Paris Distraction Symposium
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2009-09-26
    • Related Report
      2011 Final Research Report
  • [Presentation] Testing the utility of rationally engineered recombinant collagen-like proteins for applications of bone regeneration in tissue engineering2009

    • Author(s)
      Hattori H, Sieron A L, Oda T, Hibi H, UedaM, Fertala A.
    • Organizer
      World conference on regenerative medicine
    • Place of Presentation
      Leipzig, Germany
    • Related Report
      2011 Final Research Report
  • [Book] 今日の治療指針2011

    • Author(s)
      小田知生, 他
    • Publisher
      医学書院
    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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