Development of the Dental Ceramic Material with Ca modified TiO_2 Nano-tubes

• Project/Area Number: 21791956
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Osaka Dental University
• Principal Investigator: NISHIDA Hisataka Osaka Dental University, 歯学部, 助教 (70448116)
• Project Period (FY): 2009 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: セラミックス / 酸化チタン / ナノチューブ / 生体材料 / 骨代替材料 / 水熱合成

Research Abstract

It is reported that the bone fracture often happened at the part in which the bone replacement material was filled. This is because not only the poor mechanical strength of bone replacement materials but also the bone regeneration ability of them is inferior compared with autogenous bone. We found that TiO_2 nanotube bonded to the cell and activated osteoblast without addition of biochemical factor in previous studies. The aim of this study was to develop the materials that promote the cell bonding , proliferation and differentiation by making Ca modified TiO_2 nanotube by hydrothermal synthesis.

Research Products

• [Presentation] Making TiO2 Nanotubes Inducing Osteoblast Activation by hydrothermal synthesis. (2010)
  • Author(s): Nishida H, Sekino T, Nakamura T, Yamamoto K.
  • Organizer: ICC 3rd International Congress on Ceramics.
  • Place of Presentation: Osaka, Japan
  • Year and Date: 2010-11-14
• [Presentation] Making TiO2 Nano-Tubes Inducing Osteoblast Activation by Hydrothermal Synthesis (2010)
  • Author(s): 西田尚敬
  • Organizer: ICC 3rd International Congress on Ceramics
  • Place of Presentation: 大阪
  • Year and Date: 2010-11-14
• [Presentation] チタン金属表面における酸化チタンナノチューブの合成と生体適合性. (2009)
  • Author(s): 西田尚敬, 江草宏, 中村隆志, 矢谷博文, 山本一世.
  • Organizer: 第54回日本歯科理工学会学術講演会.
  • Place of Presentation: 鹿児島
  • Year and Date: 2009-10-01
• [Presentation] 低温化学合成法によるチタニアナノチューブの析出と生体適合性. (2009)
  • Author(s): 西田尚敬, 江草宏, 三浦治郎, 中村隆志, 矢谷博文, 山本一世.
  • Organizer: 日本補綴歯科学会第118回学術大会.
  • Place of Presentation: 京都
  • Year and Date: 2009-06-06
• [Presentation] 低温化学合成法によるチタニアナノチューブの析出と生体適合性 (2009)
  • Author(s): 西田尚敬
  • Organizer: 社団法人日本補綴歯科学会第118回学術大会
  • Place of Presentation: 京都
• [Presentation] チタン金属表面における酸化チタンナノチューブの合成と生体適合性 (2009)
  • Author(s): 西田尚敬
  • Organizer: 平成21年度秋期(第54回)日本歯科理工学会学術講演会
  • Place of Presentation: 鹿児島