Lidocaine iontophoresis using alternating current Development of the device for patient controlled analgesia-
| Project/Area Number |
21791979
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
ANDO Shizuka Tokyo Medical and Dental University, 歯学部附属病院, 医員 (20516306)
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| Co-Investigator(Kenkyū-buntansha) |
UMINO Masahiro TTI, エルビュー株式会社 (90014125)
FUKAYAMA Haruhisa 東京医科歯科大学, 歯学部附属病院, 教授
WAKITA Ryo 東京医科歯科大学, 歯学部附属病院, 助教 (60376712)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | イオントフォレーシス / 交流通電 / 矩形波 / 浸透効率 / リドカイン / アルギン酸ゲル / AC-IOP |
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| Research Abstract |
Transdermal iontophoresis has been used for both local and systemic drug delivery. The iontophoresis of anesthetics and analgesics is used for the management of postoperative pain or cancer pain. However, some adverse effects, including electrical burns or erythema as a result of electrode polarization during electrolysis, have been reported in clinical situations. We examined the conditions of the electricity which transport lidocaine efficiently and reduce the side effects. Our purpose is to develop the transdermal patient controlled analgesia system.
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Report
(3 results)
Research Products
(6 results)
