The participation of micro RNA acquiring the ability with high-invasiveness via Epithelial-mesenchymal Transition in squamous cell carcinoma
| Project/Area Number |
21791999
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
ONO Shigehiro Hiroshima University, 大学院・医歯薬学総合研究科, 助教 (70379882)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 臨床腫瘍学 / 口腔扁平上皮癌 / 遺伝子 / 抗癌剤 / 上皮・間葉移行 / 浸潤・転移 / 口腔癌 / 癌の浸潤・転移 / 転写因子 / 扁平上皮癌 |
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| Research Abstract |
The aim of this study was to find sigunificant microRNAs for acquiring high-invasiveness in SCC cell lines using microRNA microarrays. As a results of the investigation, I have identified 9 microRNAs related infiltration. These results suggest that identified microRNAs in this research will be candidates of a cancer therapy target.
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Report
(3 results)
Research Products
(10 results)
