Prognostic factor study of oral squmanous cell carcinomas based on copy number aberrations
| Project/Area Number |
21792002
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Yamaguchi University |
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Principal Investigator |
UCHIDA Kenichirou Yamaguchi University, 医学部付属病院, 助教 (20379986)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 口腔扁平上皮癌 / 予後マーカー / 口腔癌 |
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| Research Abstract |
The purpose of this study is to examine the constitute prognostic markers for oral squamous cell carcinomas.In FISH analysis, copy number aberrations of 8q24.2 and 3p26.3 associated with patient's prognosis. Only copy number aberrations of CHL1 was associated with patient's prognosis. RECQL4 was analyzed as a candidate gene on 8q24. Our results suggest that CHL1 and RECQL4 are constitute marker for oral squamous cell carcinoma.
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Report
(3 results)
Research Products
(35 results)
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[Presentation] 下顎骨原発性肉腫の1例2010
Author(s)
植田祐子, 内田堅一郎, 真野隆充, 片瀬直樹, 長塚 仁, 上山吉哉
Organizer
第58回日本口腔科学会中国\四国地方部会
Place of Presentation
広島
Year and Date
2010-11-06
Related Report
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